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- W2022679178 abstract "Several disorders of oxidative metabolism have been described in association with subacute necrotizing encephalomyelopathy (SNE) or Leigh syndrome. We present an eight-year-old girl with a mild spastic paraparesis and clinical deterioration on intercurrent infections. One sib died of SNE proven by autopsy. Biochemical examination of muscle tissue points to a disturbance in the process of oxidative phosphorylation due to a disturbed oxidation of NADH. The biochemical disorders associated with SNE are reviewed. The relation of SNE to the concepts of encephalomyopathy and mitochondriopathy is discussed." @default.
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- W2022679178 date "1986-02-01" @default.
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- W2022679178 title "Disturbed Oxidative Metabolism in Subacute Necrotizing Encephalomyelopathy (Leigh Syndrome)" @default.
- W2022679178 doi "https://doi.org/10.1055/s-2008-1052495" @default.
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