Matches in SemOpenAlex for { <https://semopenalex.org/work/W2022679703> ?p ?o ?g. }
Showing items 1 to 90 of
90
with 100 items per page.
- W2022679703 endingPage "106" @default.
- W2022679703 startingPage "100" @default.
- W2022679703 abstract "Apnea of prematurity is common and none of the treatments being used are fully effective and free of significant adverse side effects. We hypothesized that low concentrations of CO2 (< or = 1.5%) may reduce apnea without causing discomfort from an increase in ventilation. We studied 10 preterm infants at a gestational age of 32+/-1 wk (mean +/- SEM) and birthweight 1.8+/-0.2 kg. After a control period of 1 hour, concentrations of CO2 were given (0.5%, 1%, and 1.5%) for 1 hour each, followed by a recovery period of 1 hour. Apnea number significantly decreased from 2.0+/-0.3 apneas/min during control to 1.0+/-0.1 apneas/min (0.5% CO2; P < .05), 1.1+/-0.2 (1% CO2; P < .05), and to 0.7+/-0.2 (1.5% CO2; P < .01). The apnea time significantly decreased from 14.2+/-2.5 s/min during control to 5.2+/-0.8 (0.5% CO2; P < .01), 5.8+/-0.7 (1% CO2; P < .01), and to 3.7+/-0.9 (1.5% CO2; P < .01). Minute ventilation significantly increased with CO2 without evidence of respiratory discomfort. TcPCO2 did not change and TcPO2 increased slightly. These findings suggest that inhalation of low concentrations of CO2 in preterm infants with apnea 1) decreases the number and time of apneas, 2) improves oxygenation, 3) increases ventilation, and 4) is effective even in such low concentrations as 0.5%. We speculate that inhalation of CO2 (< 1%) is more effective and safer than methylxanthines for the treatment of apnea of prematurity." @default.
- W2022679703 created "2016-06-24" @default.
- W2022679703 creator A5013609329 @default.
- W2022679703 creator A5029604795 @default.
- W2022679703 creator A5044070818 @default.
- W2022679703 creator A5068285664 @default.
- W2022679703 creator A5078829382 @default.
- W2022679703 creator A5082742863 @default.
- W2022679703 date "2001-04-01" @default.
- W2022679703 modified "2023-10-15" @default.
- W2022679703 title "Inhalation of low (0.5%–1.5%) CO2 as a potential treatment for apnea of prematurity" @default.
- W2022679703 cites W1993634656 @default.
- W2022679703 cites W1996834925 @default.
- W2022679703 cites W2006721860 @default.
- W2022679703 cites W2018435017 @default.
- W2022679703 cites W2040078773 @default.
- W2022679703 cites W2059117859 @default.
- W2022679703 cites W2083841707 @default.
- W2022679703 cites W2086901460 @default.
- W2022679703 cites W2171217863 @default.
- W2022679703 cites W2309925718 @default.
- W2022679703 doi "https://doi.org/10.1053/sper.2001.23199" @default.
- W2022679703 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/11339662" @default.
- W2022679703 hasPublicationYear "2001" @default.
- W2022679703 type Work @default.
- W2022679703 sameAs 2022679703 @default.
- W2022679703 citedByCount "16" @default.
- W2022679703 countsByYear W20226797032012 @default.
- W2022679703 countsByYear W20226797032013 @default.
- W2022679703 countsByYear W20226797032016 @default.
- W2022679703 countsByYear W20226797032019 @default.
- W2022679703 crossrefType "journal-article" @default.
- W2022679703 hasAuthorship W2022679703A5013609329 @default.
- W2022679703 hasAuthorship W2022679703A5029604795 @default.
- W2022679703 hasAuthorship W2022679703A5044070818 @default.
- W2022679703 hasAuthorship W2022679703A5068285664 @default.
- W2022679703 hasAuthorship W2022679703A5078829382 @default.
- W2022679703 hasAuthorship W2022679703A5082742863 @default.
- W2022679703 hasConcept C126322002 @default.
- W2022679703 hasConcept C127413603 @default.
- W2022679703 hasConcept C200457457 @default.
- W2022679703 hasConcept C2776954882 @default.
- W2022679703 hasConcept C2778376644 @default.
- W2022679703 hasConcept C2779234561 @default.
- W2022679703 hasConcept C2779832335 @default.
- W2022679703 hasConcept C2781326671 @default.
- W2022679703 hasConcept C42219234 @default.
- W2022679703 hasConcept C534529494 @default.
- W2022679703 hasConcept C54355233 @default.
- W2022679703 hasConcept C70289976 @default.
- W2022679703 hasConcept C71924100 @default.
- W2022679703 hasConcept C78519656 @default.
- W2022679703 hasConcept C86803240 @default.
- W2022679703 hasConceptScore W2022679703C126322002 @default.
- W2022679703 hasConceptScore W2022679703C127413603 @default.
- W2022679703 hasConceptScore W2022679703C200457457 @default.
- W2022679703 hasConceptScore W2022679703C2776954882 @default.
- W2022679703 hasConceptScore W2022679703C2778376644 @default.
- W2022679703 hasConceptScore W2022679703C2779234561 @default.
- W2022679703 hasConceptScore W2022679703C2779832335 @default.
- W2022679703 hasConceptScore W2022679703C2781326671 @default.
- W2022679703 hasConceptScore W2022679703C42219234 @default.
- W2022679703 hasConceptScore W2022679703C534529494 @default.
- W2022679703 hasConceptScore W2022679703C54355233 @default.
- W2022679703 hasConceptScore W2022679703C70289976 @default.
- W2022679703 hasConceptScore W2022679703C71924100 @default.
- W2022679703 hasConceptScore W2022679703C78519656 @default.
- W2022679703 hasConceptScore W2022679703C86803240 @default.
- W2022679703 hasIssue "2" @default.
- W2022679703 hasLocation W20226797031 @default.
- W2022679703 hasLocation W20226797032 @default.
- W2022679703 hasOpenAccess W2022679703 @default.
- W2022679703 hasPrimaryLocation W20226797031 @default.
- W2022679703 hasRelatedWork W2022679703 @default.
- W2022679703 hasRelatedWork W2036839806 @default.
- W2022679703 hasRelatedWork W2038508968 @default.
- W2022679703 hasRelatedWork W2046206565 @default.
- W2022679703 hasRelatedWork W2087855943 @default.
- W2022679703 hasRelatedWork W2114235313 @default.
- W2022679703 hasRelatedWork W2142638823 @default.
- W2022679703 hasRelatedWork W2408932743 @default.
- W2022679703 hasRelatedWork W2412016678 @default.
- W2022679703 hasRelatedWork W3129547618 @default.
- W2022679703 hasVolume "25" @default.
- W2022679703 isParatext "false" @default.
- W2022679703 isRetracted "false" @default.
- W2022679703 magId "2022679703" @default.
- W2022679703 workType "article" @default.