FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2022679761> ?p ?o ?g. }

• W2022679761 endingPage "17366" @default.
• W2022679761 startingPage "17360" @default.
• W2022679761 abstract "GP46 is an abundant glycoprotein of 46 kDa on the surface of the promastigote form of most <i>Leishmania</i>species. We show that the steady state level of GP46 mRNA increases >30-fold as <i>Leishmania chagasi</i> promastigotes develop<i>in vitro</i> from a less infectious form during logarithmic growth to a highly infectious form in the stationary phase of cultivation. Nuclear run-on experiments demonstrate that this increase in GP46 mRNA abundance is regulated post-transcriptionally. Plasmids containing the 3′-untranslated regions (UTRs) and downstream intergenic regions (IRs) of two different GP46 genes fused immediately downstream of the β-galactosidase coding region were transfected into<i>L. chagasi</i>, and β-galactosidase activity and mRNA levels were examined. The presence of the 3′-UTR + IR of one GP46 gene (<i>gp46</i>A) resulted in a steady increase in β-galactosidase activity and mRNA level as the transfected promastigotes developed from logarithmic to stationary phase. This differential effect parallels that of the 3′-UTRs + IRs of a family of genes for an unrelated <i>Leishmania</i> surface glycoprotein, GP63. Thus, post-transcriptional regulation of the genes for two different surface glycoproteins of <i>Leishmania</i> occurs via a similar mechanism." @default.
• W2022679761 created "2016-06-24" @default.
• W2022679761 creator A5018979754 @default.
• W2022679761 creator A5052673552 @default.
• W2022679761 creator A5065325421 @default.
• W2022679761 creator A5078974968 @default.
• W2022679761 creator A5088790944 @default.
• W2022679761 date "1997-07-01" @default.
• W2022679761 modified "2023-09-30" @default.
• W2022679761 title "Glycoprotein 46 mRNA Abundance Is Post-transcriptionally Regulated during Development of Leishmania chagasiPromastigotes to an Infectious Form" @default.
• W2022679761 cites W1258546148 @default.
• W2022679761 cites W1524872354 @default.
• W2022679761 cites W1583868806 @default.
• W2022679761 cites W1592463599 @default.
• W2022679761 cites W1598257944 @default.
• W2022679761 cites W1659027529 @default.
• W2022679761 cites W1883122097 @default.
• W2022679761 cites W191134513 @default.
• W2022679761 cites W1943240551 @default.
• W2022679761 cites W1963953942 @default.
• W2022679761 cites W1966835460 @default.
• W2022679761 cites W1966864969 @default.
• W2022679761 cites W1990382291 @default.
• W2022679761 cites W2010335887 @default.
• W2022679761 cites W2014073890 @default.
• W2022679761 cites W2017438678 @default.
• W2022679761 cites W2027109238 @default.
• W2022679761 cites W2034621133 @default.
• W2022679761 cites W2035113683 @default.
• W2022679761 cites W2052095708 @default.
• W2022679761 cites W2053895943 @default.
• W2022679761 cites W2065515480 @default.
• W2022679761 cites W2066458056 @default.
• W2022679761 cites W2082417883 @default.
• W2022679761 cites W2083462655 @default.
• W2022679761 cites W2093921047 @default.
• W2022679761 cites W2102565252 @default.
• W2022679761 cites W2110255257 @default.
• W2022679761 cites W2167122322 @default.
• W2022679761 cites W2178351178 @default.
• W2022679761 cites W4294216491 @default.
• W2022679761 doi "https://doi.org/10.1074/jbc.272.28.17360" @default.
• W2022679761 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/9211875" @default.
• W2022679761 hasPublicationYear "1997" @default.
• W2022679761 type Work @default.
• W2022679761 sameAs 2022679761 @default.
• W2022679761 citedByCount "51" @default.
• W2022679761 countsByYear W20226797612012 @default.
• W2022679761 countsByYear W20226797612014 @default.
• W2022679761 countsByYear W20226797612015 @default.
• W2022679761 countsByYear W20226797612016 @default.
• W2022679761 countsByYear W20226797612018 @default.
• W2022679761 countsByYear W20226797612019 @default.
• W2022679761 crossrefType "journal-article" @default.
• W2022679761 hasAuthorship W2022679761A5018979754 @default.
• W2022679761 hasAuthorship W2022679761A5052673552 @default.
• W2022679761 hasAuthorship W2022679761A5065325421 @default.
• W2022679761 hasAuthorship W2022679761A5078974968 @default.
• W2022679761 hasAuthorship W2022679761A5088790944 @default.
• W2022679761 hasBestOaLocation W20226797611 @default.
• W2022679761 hasConcept C104317684 @default.
• W2022679761 hasConcept C105580179 @default.
• W2022679761 hasConcept C136764020 @default.
• W2022679761 hasConcept C153911025 @default.
• W2022679761 hasConcept C22744801 @default.
• W2022679761 hasConcept C2780599195 @default.
• W2022679761 hasConcept C2781092759 @default.
• W2022679761 hasConcept C41008148 @default.
• W2022679761 hasConcept C54355233 @default.
• W2022679761 hasConcept C71928629 @default.
• W2022679761 hasConcept C86803240 @default.
• W2022679761 hasConcept C89604277 @default.
• W2022679761 hasConcept C95444343 @default.
• W2022679761 hasConceptScore W2022679761C104317684 @default.
• W2022679761 hasConceptScore W2022679761C105580179 @default.
• W2022679761 hasConceptScore W2022679761C136764020 @default.
• W2022679761 hasConceptScore W2022679761C153911025 @default.
• W2022679761 hasConceptScore W2022679761C22744801 @default.
• W2022679761 hasConceptScore W2022679761C2780599195 @default.
• W2022679761 hasConceptScore W2022679761C2781092759 @default.
• W2022679761 hasConceptScore W2022679761C41008148 @default.
• W2022679761 hasConceptScore W2022679761C54355233 @default.
• W2022679761 hasConceptScore W2022679761C71928629 @default.
• W2022679761 hasConceptScore W2022679761C86803240 @default.
• W2022679761 hasConceptScore W2022679761C89604277 @default.
• W2022679761 hasConceptScore W2022679761C95444343 @default.
• W2022679761 hasIssue "28" @default.
• W2022679761 hasLocation W20226797611 @default.
• W2022679761 hasOpenAccess W2022679761 @default.
• W2022679761 hasPrimaryLocation W20226797611 @default.
• W2022679761 hasRelatedWork W1966512561 @default.
• W2022679761 hasRelatedWork W1984637510 @default.
• W2022679761 hasRelatedWork W1992114227 @default.
• W2022679761 hasRelatedWork W2000437140 @default.
• W2022679761 hasRelatedWork W2012466024 @default.
• W2022679761 hasRelatedWork W2037410803 @default.
• W2022679761 hasRelatedWork W2038160098 @default.
• W2022679761 hasRelatedWork W2063941714 @default.

• next