Matches in SemOpenAlex for { <https://semopenalex.org/work/W2022681127> ?p ?o ?g. }
Showing items 1 to 95 of
95
with 100 items per page.
- W2022681127 endingPage "37" @default.
- W2022681127 startingPage "33" @default.
- W2022681127 abstract "Hypersensitivity syndrome (HSS) reactions are one of the most feared idiosyncratic drug reactions and are most common with exposure to antiepileptic drugs (AEDs), sulfonamides, nonsteroidal antiinflammatory drugs, corticosteroids, and allopurinol. HSS is associated with chemotoxic and T-cell–mediated inflammatory injuries in barrier tissue systems that contain cytochrome oxidases (e.g., skin, mucosa, liver, and lungs) and can be seen as a derangement in the defense system against xenobiotics—bioactive foreign molecules. The mechanisms for anticonvulsant HSS are incompletely understood but involve genetic susceptibility, with accumulation of AEDs and oxidized metabolites causing major histocompatibility complex (MHC) and non–MHC–dependent clonal activation of T cells and subsequent cytokine/chemokine production in T cells, keratinocytes, and other target cells. This review discusses the classification and possible mechanisms for anticonvulsant HSS." @default.
- W2022681127 created "2016-06-24" @default.
- W2022681127 creator A5062520786 @default.
- W2022681127 date "2006-03-01" @default.
- W2022681127 modified "2023-10-01" @default.
- W2022681127 title "Current Understanding of Delayed Anticonvulsant Hypersensitivity Reactions" @default.
- W2022681127 cites W1963831154 @default.
- W2022681127 cites W1969575821 @default.
- W2022681127 cites W1979033356 @default.
- W2022681127 cites W1983129674 @default.
- W2022681127 cites W2005328285 @default.
- W2022681127 cites W2011616860 @default.
- W2022681127 cites W2014810381 @default.
- W2022681127 cites W2016310235 @default.
- W2022681127 cites W2017663330 @default.
- W2022681127 cites W2047901601 @default.
- W2022681127 cites W2049902892 @default.
- W2022681127 cites W2052110525 @default.
- W2022681127 cites W2052372045 @default.
- W2022681127 cites W2055076454 @default.
- W2022681127 cites W2061751608 @default.
- W2022681127 cites W2070486804 @default.
- W2022681127 cites W2071566315 @default.
- W2022681127 cites W2087094124 @default.
- W2022681127 cites W2101695930 @default.
- W2022681127 cites W2108686931 @default.
- W2022681127 cites W2122012588 @default.
- W2022681127 cites W2131019815 @default.
- W2022681127 cites W2321102680 @default.
- W2022681127 cites W4239128319 @default.
- W2022681127 cites W4245615997 @default.
- W2022681127 cites W90290619 @default.
- W2022681127 doi "https://doi.org/10.1111/j.1535-7511.2006.00089.x" @default.
- W2022681127 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/1408282" @default.
- W2022681127 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/16604195" @default.
- W2022681127 hasPublicationYear "2006" @default.
- W2022681127 type Work @default.
- W2022681127 sameAs 2022681127 @default.
- W2022681127 citedByCount "51" @default.
- W2022681127 countsByYear W20226811272012 @default.
- W2022681127 countsByYear W20226811272013 @default.
- W2022681127 countsByYear W20226811272014 @default.
- W2022681127 countsByYear W20226811272015 @default.
- W2022681127 countsByYear W20226811272016 @default.
- W2022681127 countsByYear W20226811272018 @default.
- W2022681127 countsByYear W20226811272019 @default.
- W2022681127 countsByYear W20226811272020 @default.
- W2022681127 countsByYear W20226811272021 @default.
- W2022681127 countsByYear W20226811272022 @default.
- W2022681127 crossrefType "journal-article" @default.
- W2022681127 hasAuthorship W2022681127A5062520786 @default.
- W2022681127 hasBestOaLocation W20226811271 @default.
- W2022681127 hasConcept C118552586 @default.
- W2022681127 hasConcept C13373296 @default.
- W2022681127 hasConcept C203014093 @default.
- W2022681127 hasConcept C207936829 @default.
- W2022681127 hasConcept C2775858608 @default.
- W2022681127 hasConcept C2778186239 @default.
- W2022681127 hasConcept C2778484676 @default.
- W2022681127 hasConcept C71924100 @default.
- W2022681127 hasConcept C8891405 @default.
- W2022681127 hasConcept C98274493 @default.
- W2022681127 hasConceptScore W2022681127C118552586 @default.
- W2022681127 hasConceptScore W2022681127C13373296 @default.
- W2022681127 hasConceptScore W2022681127C203014093 @default.
- W2022681127 hasConceptScore W2022681127C207936829 @default.
- W2022681127 hasConceptScore W2022681127C2775858608 @default.
- W2022681127 hasConceptScore W2022681127C2778186239 @default.
- W2022681127 hasConceptScore W2022681127C2778484676 @default.
- W2022681127 hasConceptScore W2022681127C71924100 @default.
- W2022681127 hasConceptScore W2022681127C8891405 @default.
- W2022681127 hasConceptScore W2022681127C98274493 @default.
- W2022681127 hasIssue "2" @default.
- W2022681127 hasLocation W20226811271 @default.
- W2022681127 hasLocation W20226811272 @default.
- W2022681127 hasLocation W20226811273 @default.
- W2022681127 hasOpenAccess W2022681127 @default.
- W2022681127 hasPrimaryLocation W20226811271 @default.
- W2022681127 hasRelatedWork W1994222673 @default.
- W2022681127 hasRelatedWork W2005666125 @default.
- W2022681127 hasRelatedWork W2038483502 @default.
- W2022681127 hasRelatedWork W2050374169 @default.
- W2022681127 hasRelatedWork W2158034307 @default.
- W2022681127 hasRelatedWork W2217141933 @default.
- W2022681127 hasRelatedWork W2397731726 @default.
- W2022681127 hasRelatedWork W4242670016 @default.
- W2022681127 hasRelatedWork W4244152674 @default.
- W2022681127 hasRelatedWork W4256626468 @default.
- W2022681127 hasVolume "6" @default.
- W2022681127 isParatext "false" @default.
- W2022681127 isRetracted "false" @default.
- W2022681127 magId "2022681127" @default.
- W2022681127 workType "article" @default.