FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2022683182> ?p ?o ?g. }

• W2022683182 endingPage "144" @default.
• W2022683182 startingPage "139" @default.
• W2022683182 abstract "Pycnogenol (procyanidins extracted from Pinus maritima) has been reputed as a potent free-radical scavenger and an antioxidant phytochemical. We previously reported that pycnogenol prevents vascular endothelial cells from injury induced by an organic oxidant t-butyl hydroperoxide. In this study, we determined the effects of pycnogenol on (a) oxidative burst of macrophages, (b) oxidation of plasma low density lipoprotein (LDL), and (c) hydroxyl radical-induced breakage of plasmid DNA. Pycnogenol was incubated with J774 murine macrophages at 37°C and 5% CO2 and oxidative burst was triggered by zymosan. The intensity of fluorescence was measured. Pycnogenol exhibited a concentration-dependent inhibition of oxidative burst. CuSO4 was used to oxidize human plasma LDL and the formation of thiobarbituric acid reactive substances (TBARS) was determined. Co-incubation with pycnogenol resulted in a concentration-dependent inhibition of LDL oxidation. Exposure ofpBR322 plasmid DNA to iron/ascorbic acid system resulted in cleavage/damage of DNA by hydroxyl radical, measured by agarose gel electrophoresis. Pycnogenol significantly minimized this cleavage. The results indicate that pycnogenol exhibits an extensive antioxidant effect in all three in vitro systems." @default.
• W2022683182 created "2016-06-24" @default.
• W2022683182 creator A5043531406 @default.
• W2022683182 creator A5049439858 @default.
• W2022683182 creator A5057792267 @default.
• W2022683182 creator A5089427558 @default.
• W2022683182 date "1998-01-01" @default.
• W2022683182 modified "2023-09-26" @default.
• W2022683182 title "Pycnogenol Inhibits Macrophage Oxidative Burst, Lipoprotein Oxidation, and Hydroxyl Radical-Induced DNA Damage" @default.
• W2022683182 cites W1775749144 @default.
• W2022683182 cites W1965731970 @default.
• W2022683182 cites W1973429989 @default.
• W2022683182 cites W1980592834 @default.
• W2022683182 cites W1981427112 @default.
• W2022683182 cites W1982544494 @default.
• W2022683182 cites W2002903565 @default.
• W2022683182 cites W2004021648 @default.
• W2022683182 cites W2006200791 @default.
• W2022683182 cites W2024146490 @default.
• W2022683182 cites W2065853122 @default.
• W2022683182 cites W2152344920 @default.
• W2022683182 cites W2164625332 @default.
• W2022683182 cites W2281560986 @default.
• W2022683182 cites W2326202471 @default.
• W2022683182 cites W3224415 @default.
• W2022683182 doi "https://doi.org/10.3109/03639049809085598" @default.
• W2022683182 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/15605443" @default.
• W2022683182 hasPublicationYear "1998" @default.
• W2022683182 type Work @default.
• W2022683182 sameAs 2022683182 @default.
• W2022683182 citedByCount "52" @default.
• W2022683182 countsByYear W20226831822012 @default.
• W2022683182 countsByYear W20226831822013 @default.
• W2022683182 countsByYear W20226831822014 @default.
• W2022683182 countsByYear W20226831822015 @default.
• W2022683182 countsByYear W20226831822016 @default.
• W2022683182 countsByYear W20226831822017 @default.
• W2022683182 countsByYear W20226831822018 @default.
• W2022683182 countsByYear W20226831822019 @default.
• W2022683182 countsByYear W20226831822021 @default.
• W2022683182 countsByYear W20226831822022 @default.
• W2022683182 crossrefType "journal-article" @default.
• W2022683182 hasAuthorship W2022683182A5043531406 @default.
• W2022683182 hasAuthorship W2022683182A5049439858 @default.
• W2022683182 hasAuthorship W2022683182A5057792267 @default.
• W2022683182 hasAuthorship W2022683182A5089427558 @default.
• W2022683182 hasConcept C139066938 @default.
• W2022683182 hasConcept C143425029 @default.
• W2022683182 hasConcept C185592680 @default.
• W2022683182 hasConcept C2776573510 @default.
• W2022683182 hasConcept C2776778087 @default.
• W2022683182 hasConcept C2777352226 @default.
• W2022683182 hasConcept C2777504301 @default.
• W2022683182 hasConcept C2778004101 @default.
• W2022683182 hasConcept C2778163477 @default.
• W2022683182 hasConcept C2779620165 @default.
• W2022683182 hasConcept C2780072125 @default.
• W2022683182 hasConcept C2780829032 @default.
• W2022683182 hasConcept C2781119792 @default.
• W2022683182 hasConcept C2986274086 @default.
• W2022683182 hasConcept C3020296196 @default.
• W2022683182 hasConcept C31903555 @default.
• W2022683182 hasConcept C48349386 @default.
• W2022683182 hasConcept C552990157 @default.
• W2022683182 hasConcept C55493867 @default.
• W2022683182 hasConcept C57600042 @default.
• W2022683182 hasConcept C99971728 @default.
• W2022683182 hasConceptScore W2022683182C139066938 @default.
• W2022683182 hasConceptScore W2022683182C143425029 @default.
• W2022683182 hasConceptScore W2022683182C185592680 @default.
• W2022683182 hasConceptScore W2022683182C2776573510 @default.
• W2022683182 hasConceptScore W2022683182C2776778087 @default.
• W2022683182 hasConceptScore W2022683182C2777352226 @default.
• W2022683182 hasConceptScore W2022683182C2777504301 @default.
• W2022683182 hasConceptScore W2022683182C2778004101 @default.
• W2022683182 hasConceptScore W2022683182C2778163477 @default.
• W2022683182 hasConceptScore W2022683182C2779620165 @default.
• W2022683182 hasConceptScore W2022683182C2780072125 @default.
• W2022683182 hasConceptScore W2022683182C2780829032 @default.
• W2022683182 hasConceptScore W2022683182C2781119792 @default.
• W2022683182 hasConceptScore W2022683182C2986274086 @default.
• W2022683182 hasConceptScore W2022683182C3020296196 @default.
• W2022683182 hasConceptScore W2022683182C31903555 @default.
• W2022683182 hasConceptScore W2022683182C48349386 @default.
• W2022683182 hasConceptScore W2022683182C552990157 @default.
• W2022683182 hasConceptScore W2022683182C55493867 @default.
• W2022683182 hasConceptScore W2022683182C57600042 @default.
• W2022683182 hasConceptScore W2022683182C99971728 @default.
• W2022683182 hasIssue "2" @default.
• W2022683182 hasLocation W20226831821 @default.
• W2022683182 hasLocation W20226831822 @default.
• W2022683182 hasOpenAccess W2022683182 @default.
• W2022683182 hasPrimaryLocation W20226831821 @default.
• W2022683182 hasRelatedWork W1792952403 @default.
• W2022683182 hasRelatedWork W1915982035 @default.
• W2022683182 hasRelatedWork W1978322324 @default.
• W2022683182 hasRelatedWork W1988130582 @default.
• W2022683182 hasRelatedWork W2012500071 @default.

• next