FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2022684877> ?p ?o ?g. }

• W2022684877 endingPage "361" @default.
• W2022684877 startingPage "357" @default.
• W2022684877 abstract "Previous studies have revealed that cannabinoid (CB)-receptor agonists inhibit gastric acid secretion stimulated by indirectly acting agents, but not by histamine. Aiming to investigate whether central or peripheral mechanisms are involved, the effects of the synthetic CB-receptor agonists WIN55,212-2 and HU-210, administered either intracerebroventricularly (i.c.v.) or intravenously (i.v.) to the anaesthetized rat with lumen-perfused stomach, against gastric acid secretion induced by pentagastrin were tested. Injected i.c.v., both WIN55,212-2 (50 and 100 μg/kg) and HU-210 (25, 50 and 100 μg/kg) were ineffective on either basal secretion or acid output induced by pentagastrin (7.7 μg/kg, i.v.). By contrast, i.v. injections of WIN55,212-2 (100 and 1000 μg/kg) or HU-210 (10–100 μg/kg) significantly inhibited pentagastrin-induced acid secretion, maximal reductions being 75.70 and 82.24% for WIN55,212-2 and HU-210, respectively. The gastric antisecretory effect of HU-210 was prevented by administration of the selective CB1-receptor antagonist SR141716A (1000 μg/kg, i.v.). These results show that CB1-receptors mediating inhibition of gastric acid secretion in the rat are mainly peripherally located." @default.
• W2022684877 created "2016-06-24" @default.
• W2022684877 creator A5007506466 @default.
• W2022684877 creator A5028163528 @default.
• W2022684877 creator A5060471178 @default.
• W2022684877 creator A5062308618 @default.
• W2022684877 creator A5069910449 @default.
• W2022684877 creator A5078818380 @default.
• W2022684877 creator A5080407955 @default.
• W2022684877 date "2004-12-01" @default.
• W2022684877 modified "2023-10-17" @default.
• W2022684877 title "Gastric antisecretory effects of synthetic cannabinoids after central or peripheral administration in the rat" @default.
• W2022684877 cites W1507972361 @default.
• W2022684877 cites W1546587342 @default.
• W2022684877 cites W1973418737 @default.
• W2022684877 cites W1983968040 @default.
• W2022684877 cites W1990233945 @default.
• W2022684877 cites W2001972689 @default.
• W2022684877 cites W2006706324 @default.
• W2022684877 cites W2006980904 @default.
• W2022684877 cites W2009130932 @default.
• W2022684877 cites W2009864778 @default.
• W2022684877 cites W2016117931 @default.
• W2022684877 cites W2016205664 @default.
• W2022684877 cites W2018280327 @default.
• W2022684877 cites W2025369248 @default.
• W2022684877 cites W2025390026 @default.
• W2022684877 cites W2034433367 @default.
• W2022684877 cites W2043005695 @default.
• W2022684877 cites W2048312502 @default.
• W2022684877 cites W2049836728 @default.
• W2022684877 cites W2056225586 @default.
• W2022684877 cites W2057133455 @default.
• W2022684877 cites W2060694966 @default.
• W2022684877 cites W2069608144 @default.
• W2022684877 cites W2069895337 @default.
• W2022684877 cites W2079291209 @default.
• W2022684877 cites W2081941553 @default.
• W2022684877 cites W2093108172 @default.
• W2022684877 cites W2112924959 @default.
• W2022684877 cites W2156019215 @default.
• W2022684877 cites W2157518435 @default.
• W2022684877 cites W4244975272 @default.
• W2022684877 doi "https://doi.org/10.1016/j.brainresbull.2004.09.004" @default.
• W2022684877 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/15561471" @default.
• W2022684877 hasPublicationYear "2004" @default.
• W2022684877 type Work @default.
• W2022684877 sameAs 2022684877 @default.
• W2022684877 citedByCount "25" @default.
• W2022684877 countsByYear W20226848772013 @default.
• W2022684877 countsByYear W20226848772014 @default.
• W2022684877 countsByYear W20226848772015 @default.
• W2022684877 countsByYear W20226848772016 @default.
• W2022684877 countsByYear W20226848772017 @default.
• W2022684877 countsByYear W20226848772018 @default.
• W2022684877 countsByYear W20226848772020 @default.
• W2022684877 countsByYear W20226848772021 @default.
• W2022684877 crossrefType "journal-article" @default.
• W2022684877 hasAuthorship W2022684877A5007506466 @default.
• W2022684877 hasAuthorship W2022684877A5028163528 @default.
• W2022684877 hasAuthorship W2022684877A5060471178 @default.
• W2022684877 hasAuthorship W2022684877A5062308618 @default.
• W2022684877 hasAuthorship W2022684877A5069910449 @default.
• W2022684877 hasAuthorship W2022684877A5078818380 @default.
• W2022684877 hasAuthorship W2022684877A5080407955 @default.
• W2022684877 hasConcept C1122143 @default.
• W2022684877 hasConcept C126322002 @default.
• W2022684877 hasConcept C134018914 @default.
• W2022684877 hasConcept C148001335 @default.
• W2022684877 hasConcept C170493617 @default.
• W2022684877 hasConcept C185592680 @default.
• W2022684877 hasConcept C2776885963 @default.
• W2022684877 hasConcept C2777504413 @default.
• W2022684877 hasConcept C2778122271 @default.
• W2022684877 hasConcept C2779377912 @default.
• W2022684877 hasConcept C2780871563 @default.
• W2022684877 hasConcept C49039625 @default.
• W2022684877 hasConcept C71924100 @default.
• W2022684877 hasConcept C98274493 @default.
• W2022684877 hasConceptScore W2022684877C1122143 @default.
• W2022684877 hasConceptScore W2022684877C126322002 @default.
• W2022684877 hasConceptScore W2022684877C134018914 @default.
• W2022684877 hasConceptScore W2022684877C148001335 @default.
• W2022684877 hasConceptScore W2022684877C170493617 @default.
• W2022684877 hasConceptScore W2022684877C185592680 @default.
• W2022684877 hasConceptScore W2022684877C2776885963 @default.
• W2022684877 hasConceptScore W2022684877C2777504413 @default.
• W2022684877 hasConceptScore W2022684877C2778122271 @default.
• W2022684877 hasConceptScore W2022684877C2779377912 @default.
• W2022684877 hasConceptScore W2022684877C2780871563 @default.
• W2022684877 hasConceptScore W2022684877C49039625 @default.
• W2022684877 hasConceptScore W2022684877C71924100 @default.
• W2022684877 hasConceptScore W2022684877C98274493 @default.
• W2022684877 hasIssue "4" @default.
• W2022684877 hasLocation W20226848771 @default.
• W2022684877 hasOpenAccess W2022684877 @default.
• W2022684877 hasPrimaryLocation W20226848771 @default.
• W2022684877 hasRelatedWork W1992813613 @default.

• next