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• W2022689591 endingPage "2763" @default.
• W2022689591 startingPage "2750" @default.
• W2022689591 abstract "Retinylidene photoreceptors are ubiquitously present in marine protists as first documented by the identification of green proteorhodopsin (GPR). We present a detailed investigation of a rhodopsin from the protist Oxyrrhis marina (OR1) with respect to its spectroscopic properties and to its vectorial proton transport. Despite its homology to GPR, OR1’s features differ markedly in its pH dependence. Protonation of the proton acceptor starts at pH below 4 and is sensitive to the ionic conditions. The mutation of a conserved histidine H62 did not influence the pKa value in a similar manner as in other proteorhodopsins where the charged histidine interacts with the proton acceptor forming the so-called His-Asp cluster. Mutational and pH-induced effects were further reflected in the temporal behavior upon light excitation ranging from femtoseconds to seconds. The primary photodynamics exhibits a high sensitivity to the environment of the proton acceptor D100 that are correlated to the different initial states. The mutation of the H62 does not affect photoisomerization at neutral pH. This is in agreement with NMR data indicating the absence of the His-Asp cluster. The subsequent steps in the photocycle revealed protonation reactions at the Schiff base coupled to proton pumping even at low pH. The main electrogenic steps are associated with the reprotonation of the Schiff base and internal proton donor. Hence, OR1 shows a different theme of the His-Asp organization where the low pKa of the proton acceptor is not dominated by this interaction, but by other electrostatic factors." @default.
• W2022689591 created "2016-06-24" @default.
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• W2022689591 date "2013-04-15" @default.
• W2022689591 modified "2023-09-26" @default.
• W2022689591 title "Photocycle and Vectorial Proton Transfer in a Rhodopsin from the Eukaryote <i>Oxyrrhis marina</i>" @default.
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• W2022689591 cites W1967636847 @default.
• W2022689591 cites W1973906711 @default.
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• W2022689591 cites W2031880433 @default.
• W2022689591 cites W2037428481 @default.
• W2022689591 cites W2043417946 @default.
• W2022689591 cites W2047161649 @default.
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• W2022689591 cites W2051535344 @default.
• W2022689591 cites W2053811816 @default.
• W2022689591 cites W2058488568 @default.
• W2022689591 cites W2060716559 @default.
• W2022689591 cites W2060847850 @default.
• W2022689591 cites W2061689686 @default.
• W2022689591 cites W2062021082 @default.
• W2022689591 cites W2070042548 @default.
• W2022689591 cites W2072241820 @default.
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• W2022689591 cites W2075406469 @default.
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• W2022689591 cites W2087311176 @default.
• W2022689591 cites W2111254472 @default.
• W2022689591 cites W2119246165 @default.
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• W2022689591 doi "https://doi.org/10.1021/bi301412n" @default.
• W2022689591 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23586665" @default.
• W2022689591 hasPublicationYear "2013" @default.
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