Matches in SemOpenAlex for { <https://semopenalex.org/work/W2022691878> ?p ?o ?g. }
Showing items 1 to 74 of
74
with 100 items per page.
- W2022691878 endingPage "902" @default.
- W2022691878 startingPage "898" @default.
- W2022691878 abstract "Acute myeloid leukaemia (AML) cells from some individuals rapidly undergo apoptosis during in vitro culture. We have analysed this mode of cell death in AML cells harvested from patients at initial presentation and during subsequent treatment/relapse. Using flow cytometric analysis of propidium iodide-stained cells and quantitation of the subdiploid apoptotic peak, we observed that leukaemic cells from patients with AML displayed a heterogenous susceptibility to apoptosis in terms of the rate of accumulation of apoptotic cells. After 48 h incubation in the absence of added serum or exogenous growth factors the percentage of apoptotic cells ranged from 3% to 99%. This susceptibility to apoptosis correlated significantly with intracellular expression of hsp70 (P = 0.009), but not hsp90, and was also associated with the presence of p53 and low levels of expression of bcl-2." @default.
- W2022691878 created "2016-06-24" @default.
- W2022691878 creator A5014356457 @default.
- W2022691878 creator A5077314918 @default.
- W2022691878 creator A5087675019 @default.
- W2022691878 date "1996-06-01" @default.
- W2022691878 modified "2023-10-18" @default.
- W2022691878 title "Susceptibility of AML cells to <i>in vitro</i> apoptosis correlates with heat shock protein 70 (hsp70) expression" @default.
- W2022691878 doi "https://doi.org/10.1046/j.1365-2141.1996.d01-1737.x" @default.
- W2022691878 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/8703823" @default.
- W2022691878 hasPublicationYear "1996" @default.
- W2022691878 type Work @default.
- W2022691878 sameAs 2022691878 @default.
- W2022691878 citedByCount "40" @default.
- W2022691878 countsByYear W20226918782012 @default.
- W2022691878 countsByYear W20226918782014 @default.
- W2022691878 countsByYear W20226918782019 @default.
- W2022691878 countsByYear W20226918782023 @default.
- W2022691878 crossrefType "journal-article" @default.
- W2022691878 hasAuthorship W2022691878A5014356457 @default.
- W2022691878 hasAuthorship W2022691878A5077314918 @default.
- W2022691878 hasAuthorship W2022691878A5087675019 @default.
- W2022691878 hasConcept C104317684 @default.
- W2022691878 hasConcept C153911025 @default.
- W2022691878 hasConcept C190283241 @default.
- W2022691878 hasConcept C202751555 @default.
- W2022691878 hasConcept C203014093 @default.
- W2022691878 hasConcept C205260736 @default.
- W2022691878 hasConcept C2775934118 @default.
- W2022691878 hasConcept C31573885 @default.
- W2022691878 hasConcept C502942594 @default.
- W2022691878 hasConcept C553184892 @default.
- W2022691878 hasConcept C55493867 @default.
- W2022691878 hasConcept C68991219 @default.
- W2022691878 hasConcept C79879829 @default.
- W2022691878 hasConcept C86803240 @default.
- W2022691878 hasConcept C95444343 @default.
- W2022691878 hasConceptScore W2022691878C104317684 @default.
- W2022691878 hasConceptScore W2022691878C153911025 @default.
- W2022691878 hasConceptScore W2022691878C190283241 @default.
- W2022691878 hasConceptScore W2022691878C202751555 @default.
- W2022691878 hasConceptScore W2022691878C203014093 @default.
- W2022691878 hasConceptScore W2022691878C205260736 @default.
- W2022691878 hasConceptScore W2022691878C2775934118 @default.
- W2022691878 hasConceptScore W2022691878C31573885 @default.
- W2022691878 hasConceptScore W2022691878C502942594 @default.
- W2022691878 hasConceptScore W2022691878C553184892 @default.
- W2022691878 hasConceptScore W2022691878C55493867 @default.
- W2022691878 hasConceptScore W2022691878C68991219 @default.
- W2022691878 hasConceptScore W2022691878C79879829 @default.
- W2022691878 hasConceptScore W2022691878C86803240 @default.
- W2022691878 hasConceptScore W2022691878C95444343 @default.
- W2022691878 hasIssue "4" @default.
- W2022691878 hasLocation W20226918781 @default.
- W2022691878 hasLocation W20226918782 @default.
- W2022691878 hasOpenAccess W2022691878 @default.
- W2022691878 hasPrimaryLocation W20226918781 @default.
- W2022691878 hasRelatedWork W2003602567 @default.
- W2022691878 hasRelatedWork W2005856601 @default.
- W2022691878 hasRelatedWork W2060924028 @default.
- W2022691878 hasRelatedWork W2328524531 @default.
- W2022691878 hasRelatedWork W2355064692 @default.
- W2022691878 hasRelatedWork W2365320098 @default.
- W2022691878 hasRelatedWork W2368770009 @default.
- W2022691878 hasRelatedWork W2375889511 @default.
- W2022691878 hasRelatedWork W2379624126 @default.
- W2022691878 hasRelatedWork W2391207083 @default.
- W2022691878 hasVolume "93" @default.
- W2022691878 isParatext "false" @default.
- W2022691878 isRetracted "false" @default.
- W2022691878 magId "2022691878" @default.
- W2022691878 workType "article" @default.