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- W2022697750 abstract "The complete nucleotide sequence of the human influenza A/Victoria/3/75 neuraminidase gene was determined using a double-stranded DNA copy of the gene, cloned in plasmid pBR322. This neuraminidase gene codes for 469 amino acids, adding up to an unglycosylated molecular weight of 52,175. A comparison is made for the first time of the complete primary structures of the two known human influenza neuraminidase subtypes. The amount of variation between the neuraminidase subtypes is similar to the well-documented variation between subtypes of the other influenza surface antigen, the haemagglutinin. A tentative prediction is made of the location of some antigenic determinants on the neuraminidase using, among other methods, an analysis of the hydrophilicity profile." @default.
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- W2022697750 date "1982-10-01" @default.
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- W2022697750 title "Complete nucleotide sequence of a human influenza neuraminidase gene of subtype N2 (A/Victoria/3/75)" @default.
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- W2022697750 doi "https://doi.org/10.1016/0022-2836(82)90274-1" @default.
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