Matches in SemOpenAlex for { <https://semopenalex.org/work/W2022698380> ?p ?o ?g. }
Showing items 1 to 79 of
79
with 100 items per page.
- W2022698380 endingPage "145" @default.
- W2022698380 startingPage "138" @default.
- W2022698380 abstract "Important advances in our understanding of the regulation of hepatic apolipoprotein B secretion have been made in the past year. A diverse group of studies have provided evidence that the inhibition of cholesterol synthesis by 3-hydroxy-3-methylglutaryl-coenzyme A reductase inhibitors decreases the hepatic assembly and secretion of apolipoprotein B-containing lipoproteins. Apolipoprotein B kinetic studies performed in animals and human individuals indicate that inhibition of VLDL-apolipoprotein B secretion is an important mechanism whereby reductase inhibitors decrease plasma concentrations of these lipoproteins. Studies in cultured hepatocytes and in-vivo animal models have provided insights into how reduction of cholesterol synthesis decreases apolipoprotein B secretion. A decrease in hepatic acyl-coenzyme A: cholesterol acyltransferase activity, secondary to reduced microsomal cholesterol concentrations, has been implicated." @default.
- W2022698380 created "2016-06-24" @default.
- W2022698380 creator A5006036283 @default.
- W2022698380 creator A5046009433 @default.
- W2022698380 date "1997-06-01" @default.
- W2022698380 modified "2023-10-14" @default.
- W2022698380 title "3-Hydroxy-3-methylglutaryl coenzyme A reductase inhibitors and hepatic apolipoprotein B secretion" @default.
- W2022698380 doi "https://doi.org/10.1097/00041433-199706000-00003" @default.
- W2022698380 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/9211061" @default.
- W2022698380 hasPublicationYear "1997" @default.
- W2022698380 type Work @default.
- W2022698380 sameAs 2022698380 @default.
- W2022698380 citedByCount "98" @default.
- W2022698380 countsByYear W20226983802012 @default.
- W2022698380 countsByYear W20226983802013 @default.
- W2022698380 countsByYear W20226983802015 @default.
- W2022698380 countsByYear W20226983802016 @default.
- W2022698380 countsByYear W20226983802019 @default.
- W2022698380 countsByYear W20226983802020 @default.
- W2022698380 countsByYear W20226983802022 @default.
- W2022698380 crossrefType "journal-article" @default.
- W2022698380 hasAuthorship W2022698380A5006036283 @default.
- W2022698380 hasAuthorship W2022698380A5046009433 @default.
- W2022698380 hasConcept C104950815 @default.
- W2022698380 hasConcept C126322002 @default.
- W2022698380 hasConcept C134018914 @default.
- W2022698380 hasConcept C134651460 @default.
- W2022698380 hasConcept C181199279 @default.
- W2022698380 hasConcept C185592680 @default.
- W2022698380 hasConcept C2778163477 @default.
- W2022698380 hasConcept C2779123261 @default.
- W2022698380 hasConcept C2780072125 @default.
- W2022698380 hasConcept C37002583 @default.
- W2022698380 hasConcept C49039625 @default.
- W2022698380 hasConcept C55493867 @default.
- W2022698380 hasConcept C56623246 @default.
- W2022698380 hasConcept C62746215 @default.
- W2022698380 hasConcept C71924100 @default.
- W2022698380 hasConcept C8243546 @default.
- W2022698380 hasConcept C86803240 @default.
- W2022698380 hasConceptScore W2022698380C104950815 @default.
- W2022698380 hasConceptScore W2022698380C126322002 @default.
- W2022698380 hasConceptScore W2022698380C134018914 @default.
- W2022698380 hasConceptScore W2022698380C134651460 @default.
- W2022698380 hasConceptScore W2022698380C181199279 @default.
- W2022698380 hasConceptScore W2022698380C185592680 @default.
- W2022698380 hasConceptScore W2022698380C2778163477 @default.
- W2022698380 hasConceptScore W2022698380C2779123261 @default.
- W2022698380 hasConceptScore W2022698380C2780072125 @default.
- W2022698380 hasConceptScore W2022698380C37002583 @default.
- W2022698380 hasConceptScore W2022698380C49039625 @default.
- W2022698380 hasConceptScore W2022698380C55493867 @default.
- W2022698380 hasConceptScore W2022698380C56623246 @default.
- W2022698380 hasConceptScore W2022698380C62746215 @default.
- W2022698380 hasConceptScore W2022698380C71924100 @default.
- W2022698380 hasConceptScore W2022698380C8243546 @default.
- W2022698380 hasConceptScore W2022698380C86803240 @default.
- W2022698380 hasIssue "3" @default.
- W2022698380 hasLocation W20226983801 @default.
- W2022698380 hasLocation W20226983802 @default.
- W2022698380 hasOpenAccess W2022698380 @default.
- W2022698380 hasPrimaryLocation W20226983801 @default.
- W2022698380 hasRelatedWork W1575445194 @default.
- W2022698380 hasRelatedWork W1966834268 @default.
- W2022698380 hasRelatedWork W2008892820 @default.
- W2022698380 hasRelatedWork W2011350818 @default.
- W2022698380 hasRelatedWork W2022698380 @default.
- W2022698380 hasRelatedWork W2025648868 @default.
- W2022698380 hasRelatedWork W2027447562 @default.
- W2022698380 hasRelatedWork W2042420983 @default.
- W2022698380 hasRelatedWork W2061615588 @default.
- W2022698380 hasRelatedWork W2069359810 @default.
- W2022698380 hasVolume "8" @default.
- W2022698380 isParatext "false" @default.
- W2022698380 isRetracted "false" @default.
- W2022698380 magId "2022698380" @default.
- W2022698380 workType "article" @default.