FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2022698811> ?p ?o ?g. }

• W2022698811 endingPage "49" @default.
• W2022698811 startingPage "44" @default.
• W2022698811 abstract "Background For treatment of giant perforated peptic ulcers, we hypothesized that partitioning of the gastric body instead of the antrum would prevent hypergastrinemia and minimize ulcerogenic risk. By maintaining part of the acid-secreting gastric body in continuity with the excluded distal stomach, gastrin-secreting cells in the antrum would still be inhibited by gastric acid secretion from the gastric body. Methods We studied (1) gastric body partition with gastrojejunostomy in 8 critically ill patients with giant perforated peptic ulcers and (2) the influence of gastric partition on serum gastrin in 18 dogs with gastric antral partition + gastrojejunostomy, or gastric body partition + gastrojejunostomy, or gastrotomy. Results No patient developed major postoperative complications. Serum gastrin levels were normal in 6 patients but showed an abnormal increase in 2 patients 1 month after gastric body partition. Serum gastrin levels had returned to the normal range at postoperative follow-up after 2 years. In the animal study, serum gastrin levels and the number of G-cells in the excluded antrum and acid-secreting parietal cells in the gastric body were increased when evaluated on day 60 postoperatively or after antral partition, compared with preoperative data in the same group. These changes did not occur in the group undergoing partition of the gastric body and the group undergoing gastrostomy. Postoperative serum gastrin levels, and the number of G-cells and parietal cells also was significantly greater in the antral partition group than in the other 2 groups. No ulcer was found in any dog in the gastric body partition and gastrostomy groups, but ulcers occurred in 4 dogs in the antral partition group, all of whom died of ulcer perforation. Conclusions Gastric body partition + gastrojejunostomy is a simple, dependable procedure for patients with perforated giant peptic ulcers. This procedure does not require extreme expertise and can be performed in a very short time, even by a trainee general surgeon in emergency. For treatment of giant perforated peptic ulcers, we hypothesized that partitioning of the gastric body instead of the antrum would prevent hypergastrinemia and minimize ulcerogenic risk. By maintaining part of the acid-secreting gastric body in continuity with the excluded distal stomach, gastrin-secreting cells in the antrum would still be inhibited by gastric acid secretion from the gastric body. We studied (1) gastric body partition with gastrojejunostomy in 8 critically ill patients with giant perforated peptic ulcers and (2) the influence of gastric partition on serum gastrin in 18 dogs with gastric antral partition + gastrojejunostomy, or gastric body partition + gastrojejunostomy, or gastrotomy. No patient developed major postoperative complications. Serum gastrin levels were normal in 6 patients but showed an abnormal increase in 2 patients 1 month after gastric body partition. Serum gastrin levels had returned to the normal range at postoperative follow-up after 2 years. In the animal study, serum gastrin levels and the number of G-cells in the excluded antrum and acid-secreting parietal cells in the gastric body were increased when evaluated on day 60 postoperatively or after antral partition, compared with preoperative data in the same group. These changes did not occur in the group undergoing partition of the gastric body and the group undergoing gastrostomy. Postoperative serum gastrin levels, and the number of G-cells and parietal cells also was significantly greater in the antral partition group than in the other 2 groups. No ulcer was found in any dog in the gastric body partition and gastrostomy groups, but ulcers occurred in 4 dogs in the antral partition group, all of whom died of ulcer perforation. Gastric body partition + gastrojejunostomy is a simple, dependable procedure for patients with perforated giant peptic ulcers. This procedure does not require extreme expertise and can be performed in a very short time, even by a trainee general surgeon in emergency." @default.
• W2022698811 created "2016-06-24" @default.
• W2022698811 creator A5003727292 @default.
• W2022698811 creator A5017984118 @default.
• W2022698811 creator A5062330195 @default.
• W2022698811 creator A5072571883 @default.
• W2022698811 creator A5073321237 @default.
• W2022698811 creator A5084505020 @default.
• W2022698811 date "2006-07-01" @default.
• W2022698811 modified "2023-10-17" @default.
• W2022698811 title "Gastric body partition to avoid ulcerogenic risk and hypergastrinemia" @default.
• W2022698811 cites W1968532898 @default.
• W2022698811 cites W1977966474 @default.
• W2022698811 cites W1978101050 @default.
• W2022698811 cites W2053646381 @default.
• W2022698811 cites W2067875202 @default.
• W2022698811 cites W2072021672 @default.
• W2022698811 cites W2083225955 @default.
• W2022698811 cites W2092068061 @default.
• W2022698811 cites W2106941662 @default.
• W2022698811 cites W2149372152 @default.
• W2022698811 cites W2149676875 @default.
• W2022698811 cites W2415141769 @default.
• W2022698811 cites W4231270193 @default.
• W2022698811 cites W4298404996 @default.
• W2022698811 doi "https://doi.org/10.1016/j.surg.2006.01.017" @default.
• W2022698811 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/16857441" @default.
• W2022698811 hasPublicationYear "2006" @default.
• W2022698811 type Work @default.
• W2022698811 sameAs 2022698811 @default.
• W2022698811 citedByCount "2" @default.
• W2022698811 countsByYear W20226988112017 @default.
• W2022698811 countsByYear W20226988112021 @default.
• W2022698811 crossrefType "journal-article" @default.
• W2022698811 hasAuthorship W2022698811A5003727292 @default.
• W2022698811 hasAuthorship W2022698811A5017984118 @default.
• W2022698811 hasAuthorship W2022698811A5062330195 @default.
• W2022698811 hasAuthorship W2022698811A5072571883 @default.
• W2022698811 hasAuthorship W2022698811A5073321237 @default.
• W2022698811 hasAuthorship W2022698811A5084505020 @default.
• W2022698811 hasConcept C119811328 @default.
• W2022698811 hasConcept C126322002 @default.
• W2022698811 hasConcept C131253125 @default.
• W2022698811 hasConcept C2776986829 @default.
• W2022698811 hasConcept C2777504413 @default.
• W2022698811 hasConcept C2779422922 @default.
• W2022698811 hasConcept C2910480513 @default.
• W2022698811 hasConcept C3017563778 @default.
• W2022698811 hasConcept C49039625 @default.
• W2022698811 hasConcept C71924100 @default.
• W2022698811 hasConcept C90924648 @default.
• W2022698811 hasConceptScore W2022698811C119811328 @default.
• W2022698811 hasConceptScore W2022698811C126322002 @default.
• W2022698811 hasConceptScore W2022698811C131253125 @default.
• W2022698811 hasConceptScore W2022698811C2776986829 @default.
• W2022698811 hasConceptScore W2022698811C2777504413 @default.
• W2022698811 hasConceptScore W2022698811C2779422922 @default.
• W2022698811 hasConceptScore W2022698811C2910480513 @default.
• W2022698811 hasConceptScore W2022698811C3017563778 @default.
• W2022698811 hasConceptScore W2022698811C49039625 @default.
• W2022698811 hasConceptScore W2022698811C71924100 @default.
• W2022698811 hasConceptScore W2022698811C90924648 @default.
• W2022698811 hasIssue "1" @default.
• W2022698811 hasLocation W20226988111 @default.
• W2022698811 hasLocation W20226988112 @default.
• W2022698811 hasOpenAccess W2022698811 @default.
• W2022698811 hasPrimaryLocation W20226988111 @default.
• W2022698811 hasRelatedWork W1980582514 @default.
• W2022698811 hasRelatedWork W2044102906 @default.
• W2022698811 hasRelatedWork W2087437997 @default.
• W2022698811 hasRelatedWork W2095853503 @default.
• W2022698811 hasRelatedWork W2116508232 @default.
• W2022698811 hasRelatedWork W2325336657 @default.
• W2022698811 hasRelatedWork W2411451530 @default.
• W2022698811 hasRelatedWork W2415345280 @default.
• W2022698811 hasRelatedWork W2424403311 @default.
• W2022698811 hasRelatedWork W2460225913 @default.
• W2022698811 hasVolume "140" @default.
• W2022698811 isParatext "false" @default.
• W2022698811 isRetracted "false" @default.
• W2022698811 magId "2022698811" @default.
• W2022698811 workType "article" @default.