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- W2022700222 abstract "Due to inadequate efficacy of antidepressants, various new chemical entities and agents of natural origin have been tested for therapeutic efficacy both alone and to augment existing antidepressants, producing varied clinical results. This article summarizes the basic properties of curcumin and its mechanisms of action, with specific emphasis on the etiopathogenesis of depression, preclinical and current clinical evidence, and future research directions, to better understand the possible role of curcumin in treating depression. Curcumin may have antidepressant activities with diverse mechanisms of action involving primarily neurotransmitters, transcription pathways, neurogenesis, the hypothalamic-pituitary-adrenal axis and inflammatory and immune pathways, as demonstrated in various animal and human studies. Current published randomized clinical trials suggest a small, non-significant benefit of curcumin for major depression. More adequately-powered and methodologically improved studies are mandatory." @default.
- W2022700222 created "2016-06-24" @default.
- W2022700222 creator A5014159879 @default.
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- W2022700222 creator A5041007677 @default.
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- W2022700222 creator A5084299599 @default.
- W2022700222 date "2015-02-03" @default.
- W2022700222 modified "2023-09-23" @default.
- W2022700222 title "Curcumin as a putative antidepressant" @default.
- W2022700222 cites W1546686332 @default.
- W2022700222 cites W1550971723 @default.
- W2022700222 cites W1604068141 @default.
- W2022700222 cites W1769690510 @default.
- W2022700222 cites W1813628317 @default.
- W2022700222 cites W1835574744 @default.
- W2022700222 cites W1972869003 @default.
- W2022700222 cites W1974109816 @default.
- W2022700222 cites W1974390576 @default.
- W2022700222 cites W1975727668 @default.
- W2022700222 cites W1976194786 @default.
- W2022700222 cites W1976582031 @default.
- W2022700222 cites W1977920395 @default.
- W2022700222 cites W1978956008 @default.
- W2022700222 cites W1980474344 @default.
- W2022700222 cites W1983899648 @default.
- W2022700222 cites W1985438873 @default.
- W2022700222 cites W1986211748 @default.
- W2022700222 cites W1990487655 @default.
- W2022700222 cites W1991197498 @default.
- W2022700222 cites W1991605631 @default.
- W2022700222 cites W1992795501 @default.
- W2022700222 cites W1993028853 @default.
- W2022700222 cites W1995436838 @default.
- W2022700222 cites W1996166611 @default.
- W2022700222 cites W1997906526 @default.
- W2022700222 cites W1998021499 @default.
- W2022700222 cites W1999721747 @default.
- W2022700222 cites W2000031234 @default.
- W2022700222 cites W2000248590 @default.
- W2022700222 cites W2002491188 @default.
- W2022700222 cites W2004645471 @default.
- W2022700222 cites W2007245256 @default.
- W2022700222 cites W2008082604 @default.
- W2022700222 cites W2010167850 @default.
- W2022700222 cites W2011101770 @default.
- W2022700222 cites W2018167250 @default.
- W2022700222 cites W2019714241 @default.
- W2022700222 cites W2020788145 @default.
- W2022700222 cites W2022619682 @default.
- W2022700222 cites W2024091295 @default.
- W2022700222 cites W2025318581 @default.
- W2022700222 cites W2028704769 @default.
- W2022700222 cites W2032943011 @default.
- W2022700222 cites W2034302695 @default.
- W2022700222 cites W2034630933 @default.
- W2022700222 cites W2038535468 @default.
- W2022700222 cites W2041066771 @default.
- W2022700222 cites W2041174073 @default.
- W2022700222 cites W2044390612 @default.
- W2022700222 cites W2045253296 @default.
- W2022700222 cites W2045422537 @default.
- W2022700222 cites W2048063648 @default.
- W2022700222 cites W2048774707 @default.
- W2022700222 cites W2050179655 @default.
- W2022700222 cites W2050434337 @default.
- W2022700222 cites W2056468898 @default.
- W2022700222 cites W2056825582 @default.
- W2022700222 cites W2059668480 @default.
- W2022700222 cites W2064965507 @default.
- W2022700222 cites W2065862894 @default.
- W2022700222 cites W2067657652 @default.
- W2022700222 cites W2068080380 @default.
- W2022700222 cites W2069124726 @default.
- W2022700222 cites W2077166822 @default.
- W2022700222 cites W2078569879 @default.
- W2022700222 cites W2080333902 @default.
- W2022700222 cites W2082800001 @default.
- W2022700222 cites W2083351038 @default.
- W2022700222 cites W2084111066 @default.
- W2022700222 cites W2092032160 @default.
- W2022700222 cites W2094125739 @default.
- W2022700222 cites W2094951488 @default.
- W2022700222 cites W2095174045 @default.
- W2022700222 cites W2095852687 @default.
- W2022700222 cites W2098570599 @default.
- W2022700222 cites W2101253204 @default.
- W2022700222 cites W2109074051 @default.
- W2022700222 cites W2110111555 @default.
- W2022700222 cites W2113576996 @default.
- W2022700222 cites W2115841218 @default.
- W2022700222 cites W2123375980 @default.
- W2022700222 cites W2126829009 @default.
- W2022700222 cites W2129397604 @default.
- W2022700222 cites W2131763634 @default.
- W2022700222 cites W2132324173 @default.