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- W2022708573 abstract "OBJECTIVE: The aim of this study was to determine the incidence of monozygotic pregnancy, in our IVF blastocyst program, and the relationship with extreme multigestation (EM). DESIGN: Retrospective study in a private fertility center. MATERIALS AND METHODS: During 5 years period from January 2003 to December 2007. We were made 560 blastocyst transfers from all assisted reproductive techniques cycles: IVF, intracytoplasmic sperm injection, oocyte donation, frozen/thawed embryo transfer. To obtain blastocyst we used vitrolife sequential media, and two criteria for culture embryos to day 5: 1-) 3 or more embryos grade one, with 8 cells, on day three, 2-) at least 4 embryos grade 2 with 8 cells on day three, no more than two blastocyst were transfer. Out of these criteria we performed the embryo transfer at 72h, with no more than 3 embryos. RESULTS: In 560 blastocyst transfers we obtain 250 pregnancies, the clinical pregnancy rate was 44.6%. 9 were monozygotic pregnancy; the incidence of monozygotic pregnancy was 3.6%. CONCLUSIONS: According with other authors, the culture and transfer of no more than two embryos at blastocyst stage, result an excellent strategy to reduce the number of extreme multigestation (EM) (triplets or quadruplets) and maintain adequate pregnancy rates. The EM in Latin America registry (Registro Latinoamericano de Reproducción Asistida) during 1999 until 2003 was between 7.3% - 8.2% in contrast with 2-3% obtained by Unifertes in five years of experience. The principal contribution to EM in Unifertes were the monozygotic pregnancy. The incidence of monozygotic pregnancy (3.6%) is comparable with the results reported in the literature." @default.
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- W2022708573 date "2008-09-01" @default.
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- W2022708573 title "In vitro fertilization (IVF) program with blastocyst transfer, incidence of monozygotic pregnancy, relationship with extreme multigestation" @default.
- W2022708573 doi "https://doi.org/10.1016/j.fertnstert.2008.07.1436" @default.
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