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• W2022720370 startingPage "346" @default.
• W2022720370 abstract "Metabolic changes in cells that participate in inflammation, such as activated macrophages and T-helper 17 cells, include a shift towards enhanced glucose uptake, glycolysis and increased activity of the pentose phosphate pathway. Opposing roles in these changes for hypoxia-inducible factor 1β and AMP-activated protein kinase have been proposed. By contrast, anti-inflammatory cells, such as M2 macrophages, regulatory T cells and quiescent memory T cells, have lower glycolytic rates and higher levels of oxidative metabolism. Some anti-inflammatory agents might act by inducing, through activation of AMP-activated protein kinase, a state akin to pseudo-starvation. Altered metabolism may thus participate in the signal-directed programs that promote or inhibit inflammation." @default.
• W2022720370 created "2016-06-24" @default.
• W2022720370 creator A5046976143 @default.
• W2022720370 creator A5086513049 @default.
• W2022720370 date "2013-01-16" @default.
• W2022720370 modified "2023-10-16" @default.
• W2022720370 title "Metabolism of inflammation limited by AMPK and pseudo-starvation" @default.
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