FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2022726388> ?p ?o ?g. }

• W2022726388 endingPage "227" @default.
• W2022726388 startingPage "223" @default.
• W2022726388 abstract "The objective of this study is to evaluate the cardiac safety of pegylated liposomal doxorubicin (PLD) reaching or exceeding a cumulative dose of 550 mg/m 2 in patients with recurrent ovarian and peritoneal cancer. A total of 14 patients (11 ovarian cancer, 3 primary peritoneal cancer) who received PLD in our center between February 2004 and October 2006 met inclusion criteria of the study. PLD was administered at doses of 30 mg/m 2 together with carboplatin or 50 mg/m 2 as a single agent every 3–6 weeks. Left ventricular ejection fraction (LVEF) estimations performed by M Mode ultrasound (General Electric Vivid-3, Milwaukee, Wisconsin) and clinical cardiac status were used to detect PLD-related cardiotoxicity. The median cumulative dose of PLD was 685.5 mg/m 2 (range 552–1015 mg/m 2 ) and the median number of PLD courses was 9.5 (range 7–17). One patient had also been previously treated with conventional doxorubicin. LVEF scans were obtained on 10 of the 14 patients at the beginning of the therapy and on all patients at the end of therapy. No clinical evidence (symptoms or physical findings) of cardiac dysfunction had been observed in these patients either during active treatment or follow-up period. Despite small number of patients and lack of control group, our study suggests that the cumulative doses in excess of 550 mg/m 2 of PLD seem to not carry a significant risk of cardiomyopathy as judged by LVEF and clinical follow-up." @default.
• W2022726388 created "2016-06-24" @default.
• W2022726388 creator A5031454671 @default.
• W2022726388 creator A5032046419 @default.
• W2022726388 creator A5033424650 @default.
• W2022726388 creator A5049223881 @default.
• W2022726388 creator A5058794118 @default.
• W2022726388 creator A5088094308 @default.
• W2022726388 date "2008-01-01" @default.
• W2022726388 modified "2023-10-10" @default.
• W2022726388 title "Cardiac safety profile of pegylated liposomal doxorubicin reaching or exceeding lifetime cumulative doses of 550 mg/m²in patients with recurrent ovarian and peritoneal cancer" @default.
• W2022726388 cites W1514525963 @default.
• W2022726388 cites W1589920570 @default.
• W2022726388 cites W1835347798 @default.
• W2022726388 cites W1966943069 @default.
• W2022726388 cites W1991423414 @default.
• W2022726388 cites W2032684321 @default.
• W2022726388 cites W2038627527 @default.
• W2022726388 cites W2044421413 @default.
• W2022726388 cites W2055892918 @default.
• W2022726388 cites W2059153951 @default.
• W2022726388 cites W2063219375 @default.
• W2022726388 cites W2070825008 @default.
• W2022726388 cites W2082992386 @default.
• W2022726388 cites W2085315051 @default.
• W2022726388 cites W2091744994 @default.
• W2022726388 cites W2094733355 @default.
• W2022726388 cites W2096593771 @default.
• W2022726388 cites W2127296215 @default.
• W2022726388 cites W2132731213 @default.
• W2022726388 cites W2148845753 @default.
• W2022726388 cites W2407704719 @default.
• W2022726388 cites W2409076328 @default.
• W2022726388 cites W76963291 @default.
• W2022726388 doi "https://doi.org/10.1111/j.1525-1438.2007.00992.x" @default.
• W2022726388 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/17511800" @default.
• W2022726388 hasPublicationYear "2008" @default.
• W2022726388 type Work @default.
• W2022726388 sameAs 2022726388 @default.
• W2022726388 citedByCount "32" @default.
• W2022726388 countsByYear W20227263882013 @default.
• W2022726388 countsByYear W20227263882014 @default.
• W2022726388 countsByYear W20227263882015 @default.
• W2022726388 countsByYear W20227263882016 @default.
• W2022726388 countsByYear W20227263882017 @default.
• W2022726388 countsByYear W20227263882018 @default.
• W2022726388 countsByYear W20227263882019 @default.
• W2022726388 countsByYear W20227263882020 @default.
• W2022726388 countsByYear W20227263882021 @default.
• W2022726388 crossrefType "journal-article" @default.
• W2022726388 hasAuthorship W2022726388A5031454671 @default.
• W2022726388 hasAuthorship W2022726388A5032046419 @default.
• W2022726388 hasAuthorship W2022726388A5033424650 @default.
• W2022726388 hasAuthorship W2022726388A5049223881 @default.
• W2022726388 hasAuthorship W2022726388A5058794118 @default.
• W2022726388 hasAuthorship W2022726388A5088094308 @default.
• W2022726388 hasConcept C121608353 @default.
• W2022726388 hasConcept C126322002 @default.
• W2022726388 hasConcept C126894567 @default.
• W2022726388 hasConcept C151032500 @default.
• W2022726388 hasConcept C164705383 @default.
• W2022726388 hasConcept C2776694085 @default.
• W2022726388 hasConcept C2778198053 @default.
• W2022726388 hasConcept C2778233292 @default.
• W2022726388 hasConcept C2778239845 @default.
• W2022726388 hasConcept C2778797674 @default.
• W2022726388 hasConcept C2780427987 @default.
• W2022726388 hasConcept C2781303535 @default.
• W2022726388 hasConcept C2781451048 @default.
• W2022726388 hasConcept C2989005 @default.
• W2022726388 hasConcept C71924100 @default.
• W2022726388 hasConcept C78085059 @default.
• W2022726388 hasConceptScore W2022726388C121608353 @default.
• W2022726388 hasConceptScore W2022726388C126322002 @default.
• W2022726388 hasConceptScore W2022726388C126894567 @default.
• W2022726388 hasConceptScore W2022726388C151032500 @default.
• W2022726388 hasConceptScore W2022726388C164705383 @default.
• W2022726388 hasConceptScore W2022726388C2776694085 @default.
• W2022726388 hasConceptScore W2022726388C2778198053 @default.
• W2022726388 hasConceptScore W2022726388C2778233292 @default.
• W2022726388 hasConceptScore W2022726388C2778239845 @default.
• W2022726388 hasConceptScore W2022726388C2778797674 @default.
• W2022726388 hasConceptScore W2022726388C2780427987 @default.
• W2022726388 hasConceptScore W2022726388C2781303535 @default.
• W2022726388 hasConceptScore W2022726388C2781451048 @default.
• W2022726388 hasConceptScore W2022726388C2989005 @default.
• W2022726388 hasConceptScore W2022726388C71924100 @default.
• W2022726388 hasConceptScore W2022726388C78085059 @default.
• W2022726388 hasIssue "2" @default.
• W2022726388 hasLocation W20227263881 @default.
• W2022726388 hasLocation W20227263882 @default.
• W2022726388 hasOpenAccess W2022726388 @default.
• W2022726388 hasPrimaryLocation W20227263881 @default.
• W2022726388 hasRelatedWork W2123912484 @default.
• W2022726388 hasRelatedWork W2143449387 @default.
• W2022726388 hasRelatedWork W2385641592 @default.
• W2022726388 hasRelatedWork W2906367351 @default.
• W2022726388 hasRelatedWork W2909980364 @default.

• next