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- W2022731004 abstract "Epithelial tubes are a fundamental tissue across the metazoan phyla and provide an essential functional component of many of the major organs. Recent work in flies and mammals has begun to elucidate the cellular mechanisms driving the formation, elongation, and branching morphogenesis of epithelial tubes during development. Both forward and reverse genetic techniques have begun to identify critical molecular regulators for these processes and have revealed the conserved role of key pathways in regulating the growth and elaboration of tubular networks. In this review, we discuss the developmental programs driving the formation of branched epithelial networks, with specific emphasis on the trachea and salivary gland of Drosophila melanogaster and the mammalian lung, mammary gland, kidney, and salivary gland. We both highlight similarities in the development of these organs and attempt to identify tissue and organism specific strategies. Finally, we briefly consider how our understanding of the regulation of proliferation, apicobasal polarity, and epithelial motility during branching morphogenesis can be applied to understand the pathologic dysregulation of these same processes during metastatic cancer progression." @default.
- W2022731004 created "2016-06-24" @default.
- W2022731004 creator A5042173388 @default.
- W2022731004 creator A5084041667 @default.
- W2022731004 date "2010-05-01" @default.
- W2022731004 modified "2023-10-03" @default.
- W2022731004 title "Morphogenesis of epithelial tubes: Insights into tube formation, elongation, and elaboration" @default.
- W2022731004 cites W1225109155 @default.
- W2022731004 cites W1537380936 @default.
- W2022731004 cites W1575984269 @default.
- W2022731004 cites W1676092466 @default.
- W2022731004 cites W1781095925 @default.
- W2022731004 cites W1796060835 @default.
- W2022731004 cites W1964359283 @default.
- W2022731004 cites W1966219224 @default.
- W2022731004 cites W1969522715 @default.
- W2022731004 cites W1970544748 @default.
- W2022731004 cites W1970895551 @default.
- W2022731004 cites W1971441895 @default.
- W2022731004 cites W1972204116 @default.
- W2022731004 cites W1972889605 @default.
- W2022731004 cites W1975097039 @default.
- W2022731004 cites W1975456228 @default.
- W2022731004 cites W1976835478 @default.
- W2022731004 cites W1977767026 @default.
- W2022731004 cites W1978529327 @default.
- W2022731004 cites W1979075281 @default.
- W2022731004 cites W1979511899 @default.
- W2022731004 cites W1980696650 @default.
- W2022731004 cites W1983072511 @default.
- W2022731004 cites W1984715051 @default.
- W2022731004 cites W1987735009 @default.
- W2022731004 cites W1987817703 @default.
- W2022731004 cites W1987883454 @default.
- W2022731004 cites W1988902941 @default.
- W2022731004 cites W1990515681 @default.
- W2022731004 cites W1990725203 @default.
- W2022731004 cites W1991555797 @default.
- W2022731004 cites W1992128468 @default.
- W2022731004 cites W1992614445 @default.
- W2022731004 cites W1993335920 @default.
- W2022731004 cites W1994683536 @default.
- W2022731004 cites W1996268443 @default.
- W2022731004 cites W1996416783 @default.
- W2022731004 cites W1996788021 @default.
- W2022731004 cites W1998166790 @default.
- W2022731004 cites W1998301679 @default.
- W2022731004 cites W1998888750 @default.
- W2022731004 cites W2002919985 @default.
- W2022731004 cites W2004843760 @default.
- W2022731004 cites W2004863382 @default.
- W2022731004 cites W2005288945 @default.
- W2022731004 cites W2007191876 @default.
- W2022731004 cites W2008588429 @default.
- W2022731004 cites W2010040980 @default.
- W2022731004 cites W2010232515 @default.
- W2022731004 cites W2010816434 @default.
- W2022731004 cites W2014254693 @default.
- W2022731004 cites W2014835250 @default.
- W2022731004 cites W2015766782 @default.
- W2022731004 cites W2016779492 @default.
- W2022731004 cites W2018440302 @default.
- W2022731004 cites W2019614403 @default.
- W2022731004 cites W2020315034 @default.
- W2022731004 cites W2020690675 @default.
- W2022731004 cites W2022781536 @default.
- W2022731004 cites W2024348342 @default.
- W2022731004 cites W2027067842 @default.
- W2022731004 cites W2027513993 @default.
- W2022731004 cites W2027894846 @default.
- W2022731004 cites W2028673763 @default.
- W2022731004 cites W2028782730 @default.
- W2022731004 cites W2030317873 @default.
- W2022731004 cites W2030563325 @default.
- W2022731004 cites W2030658369 @default.
- W2022731004 cites W2031720224 @default.
- W2022731004 cites W2032461554 @default.
- W2022731004 cites W2033273681 @default.
- W2022731004 cites W2035108361 @default.
- W2022731004 cites W2036690815 @default.
- W2022731004 cites W2037876845 @default.
- W2022731004 cites W2039706860 @default.
- W2022731004 cites W2039799168 @default.
- W2022731004 cites W2040469616 @default.
- W2022731004 cites W2043840480 @default.
- W2022731004 cites W2044927450 @default.
- W2022731004 cites W2044935342 @default.
- W2022731004 cites W2045860277 @default.
- W2022731004 cites W2046518908 @default.
- W2022731004 cites W2046773136 @default.
- W2022731004 cites W2047676549 @default.
- W2022731004 cites W2048137571 @default.
- W2022731004 cites W2048969857 @default.
- W2022731004 cites W2050964782 @default.
- W2022731004 cites W2053406235 @default.
- W2022731004 cites W2055410989 @default.
- W2022731004 cites W2056466716 @default.
- W2022731004 cites W2056494900 @default.