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- W2022731145 abstract "Schistosomiasis, which is caused by the intravascular helminth Schistosoma mansoni, is a major human parasite infection affecting a number of subtropical countries [1]. The interface between host and parasite has been extensively studied with the aim of identifying targets for vaccine-induced immunological attacks. Three reports have identified major targets of immunity on the surface of the parasite as enzymes, namely a glutathione Stransferase (GST) [2], a triose phosphate isomerase (TPI) [3,4] and a glyceraldehyde-3phosphate dehydrogenase (GAPDH), a 37-kDa antigen the cDNA of which has been cloned [5]. S. rnansoni GAPDH has been characterized as a major antigen for antibodies in the sera of the most resistant subjects to schistosomiasis [6] and has been detected on intact living schistosomula by immunofluorescence [5]." @default.
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- W2022731145 date "1992-12-01" @default.
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- W2022731145 title "Complete sequence of the Schistosoma mansoni glyceraldehyde-3-phosphate dehydrogenase gene encoding a major surface antigen" @default.
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- W2022731145 doi "https://doi.org/10.1016/0166-6851(92)90184-l" @default.
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