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- W2022740023 abstract "The cerebral findings at magnetic resonance imaging in 67 transferase-deficient galactosemic patients (36 female, 31 male; median age, 10 years) are reported. Twenty-two patients had mild cerebral atrophy, eight had cerebellar atrophy, and 11 had multiple small hyperintense lesions in the cerebral white matter on T2-weighted images. The classic galactosemic patients (those without measurable transferase activity) older than 1 year of age did not show the normal dropoff in peripheral white matter signal intensity on intermediate- and T2-weighted images. The authors postulate that this abnormal signal intensity is due to altered myelin formation secondary to the inability to make sufficient and/or normal galactocerebroside." @default.
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- W2022740023 date "1992-07-01" @default.
- W2022740023 modified "2023-10-16" @default.
- W2022740023 title "Galactosemia: evaluation with MR imaging." @default.
- W2022740023 doi "https://doi.org/10.1148/radiology.184.1.1319076" @default.
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