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- W2022740099 abstract "Background: Right middle lobe syndrome (RMLS) is characterized by chronic or recurrent right middle lobe atelectasis that can lead to pulmonary infection. Pulmonary abnormalities have been report in patients with Marfan’s syndrome; however, the association with RMLS has never been documented. Case Report: A 68-year old male patient with a diagnosis of Marfan’s syndrome and history of a small right lung mass vs. scar tissue since childhood was admitted to the hospital after several weeks of productive cough and constitutional symptoms that were treated unsuccessfully with both intravenous and oral antibiotics. A computed tomography (CT) scan of the chest revealed a 9.7 × 6.7 cm right middle lung mass. A right lateral thoracotomy was performed which revealed a large abscess. The patient subsequently underwent a right middle lobe lobectomy that led to resolution of symptoms. Conclusion: Right middle lobe syndrome is chronic or recurrent collapse of right middle lobe due to extrinsic compression or intrinsic abnormalities of bronchus. In Marfan’s syndrome patients, the abnormal collagen cross-link caused by mutate fibrillin molecule produced a reduced tensile strength of pulmonary connective tissue. Therefore, Marfan’s syndrome patient has higher propensity for collapse of right middle lung that can lead to inflammation and pneumonia under certain insults. High level of suspicion with prompt diagnosis and aggressive treatment with antibiotics may be effective. However, surgical resection become necessary when medical management fails." @default.
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- W2022740099 date "2008-02-01" @default.
- W2022740099 modified "2023-09-27" @default.
- W2022740099 title "QS330. A Case of Right Middle Lobe Syndrome in Marfan’s Disease" @default.
- W2022740099 doi "https://doi.org/10.1016/j.jss.2007.12.582" @default.
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