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• W2022743956 abstract "The large cells from Mycobacterium leprae-induced granulomas in guinea pig lymph nodes were separated by Percoll discontinuous density gradient centrifugation and on a fluorescence-activated cell sorter (FACS) using cross-reacting monoclonal antibody to human MHC Class II antigens. Large Percoll-separated cells (83% Class II antigen positive and 52% macrophage-specific antigen positive) and FACS-separated cells are able to act as antigen-presenting cells for T-cell proliferation to PPD. In previous studies, macrophage antigen-positive cells consistently failed to act as accessory cells. This indicates that there is a population of accessory cells which are macrophage antigen negative and MHC Class II antigen positive present in these M. leprae-induced granulomas." @default.
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• W2022743956 date "1986-10-01" @default.
• W2022743956 modified "2023-10-18" @default.
• W2022743956 title "Accessory cell function of cells isolated from Mycobacterium leprae-induced granulomas" @default.
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• W2022743956 doi "https://doi.org/10.1016/0008-8749(86)90428-4" @default.
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