FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2022745065> ?p ?o ?g. }

• W2022745065 endingPage "44" @default.
• W2022745065 startingPage "25" @default.
• W2022745065 abstract "In contrast to healthy subjects, duodenal ulcer patients in the active phase contain large amounts of a peptide in serum and antrum which react with antiserum specific for the N-terminus, but not the C-terminus of gastrin-17. The immunochemical and chromatographic properties were similar to that of the N-terminal tridecapeptide sequence of gastrin-17. The peptide follows the clinical course of duodenal ulcer disease, as it disappears when the ulcer heals. The N-terminal tridecapeptide - lacking the bioactive tetrapeptide of gastrin-17 - is a potent inhibitor of gastric acid secretion, presumably by way of competitive antagonism to gastrin. It is suggested to participate in the regulation of gastric acid secretion in patients with active duodenal ulcer disease. To confirm the chemical structure of the peptide, antral and gastrinoma extracts were used for isolation, purification and amino acid analysis. We found two different peptides with the same N-terminus as gastrin-17, namely the previously known N-terminal tridecapeptide fragment of gastrin-17 and a new gastrin component, identical with a C-terminal glycine extended gastrin-17. Furthermore, a C-terminal glycine extended component, corresponding to each of the other molecular forms of gastrin were present. Thus, a variety of abnormally processed gastrins are synthesized and released to the circulation during the active period of duodenal ulcer disease." @default.
• W2022745065 created "2016-06-24" @default.
• W2022745065 creator A5091436033 @default.
• W2022745065 date "1984-01-01" @default.
• W2022745065 modified "2023-09-27" @default.
• W2022745065 title "Abnormally processed gastrins in active duodenal ulcer disease" @default.
• W2022745065 cites W1428747333 @default.
• W2022745065 cites W1490773291 @default.
• W2022745065 cites W1570612113 @default.
• W2022745065 cites W1587243129 @default.
• W2022745065 cites W1701021706 @default.
• W2022745065 cites W1805518045 @default.
• W2022745065 cites W1822950385 @default.
• W2022745065 cites W186887653 @default.
• W2022745065 cites W1887358204 @default.
• W2022745065 cites W1955183257 @default.
• W2022745065 cites W1964732009 @default.
• W2022745065 cites W1969041711 @default.
• W2022745065 cites W1978522408 @default.
• W2022745065 cites W1984437333 @default.
• W2022745065 cites W1985007567 @default.
• W2022745065 cites W1986288596 @default.
• W2022745065 cites W1987432578 @default.
• W2022745065 cites W1987468358 @default.
• W2022745065 cites W1988441601 @default.
• W2022745065 cites W1989507693 @default.
• W2022745065 cites W1991220178 @default.
• W2022745065 cites W1992657993 @default.
• W2022745065 cites W1997045660 @default.
• W2022745065 cites W1999662119 @default.
• W2022745065 cites W2000204315 @default.
• W2022745065 cites W2003820188 @default.
• W2022745065 cites W2008640932 @default.
• W2022745065 cites W2020766403 @default.
• W2022745065 cites W2029050852 @default.
• W2022745065 cites W2029457360 @default.
• W2022745065 cites W2031251132 @default.
• W2022745065 cites W2032073955 @default.
• W2022745065 cites W2038895370 @default.
• W2022745065 cites W2039736549 @default.
• W2022745065 cites W2041461545 @default.
• W2022745065 cites W2045863758 @default.
• W2022745065 cites W2048711451 @default.
• W2022745065 cites W2049650087 @default.
• W2022745065 cites W2059092604 @default.
• W2022745065 cites W2061354172 @default.
• W2022745065 cites W2062425161 @default.
• W2022745065 cites W2062438327 @default.
• W2022745065 cites W2064474849 @default.
• W2022745065 cites W2070766014 @default.
• W2022745065 cites W2073158060 @default.
• W2022745065 cites W2077896949 @default.
• W2022745065 cites W2079107398 @default.
• W2022745065 cites W2079730244 @default.
• W2022745065 cites W2080198272 @default.
• W2022745065 cites W2086023587 @default.
• W2022745065 cites W2090573403 @default.
• W2022745065 cites W2102253483 @default.
• W2022745065 cites W2104294445 @default.
• W2022745065 cites W2109192655 @default.
• W2022745065 cites W2117178007 @default.
• W2022745065 cites W2117210104 @default.
• W2022745065 cites W2128368562 @default.
• W2022745065 cites W2135094915 @default.
• W2022745065 cites W2143201113 @default.
• W2022745065 cites W2157823126 @default.
• W2022745065 cites W2167107576 @default.
• W2022745065 cites W2323417561 @default.
• W2022745065 cites W2331381568 @default.
• W2022745065 cites W2401185404 @default.
• W2022745065 cites W2419556349 @default.
• W2022745065 cites W2420710099 @default.
• W2022745065 cites W2428267099 @default.
• W2022745065 cites W2433856813 @default.
• W2022745065 cites W2469715404 @default.
• W2022745065 cites W2470918719 @default.
• W2022745065 cites W3022445938 @default.
• W2022745065 cites W4256434216 @default.
• W2022745065 cites W4299999058 @default.
• W2022745065 doi "https://doi.org/10.3109/00365518409088732" @default.
• W2022745065 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/6387881" @default.
• W2022745065 hasPublicationYear "1984" @default.
• W2022745065 type Work @default.
• W2022745065 sameAs 2022745065 @default.
• W2022745065 citedByCount "1" @default.
• W2022745065 crossrefType "journal-article" @default.
• W2022745065 hasAuthorship W2022745065A5091436033 @default.
• W2022745065 hasConcept C126322002 @default.
• W2022745065 hasConcept C131253125 @default.
• W2022745065 hasConcept C134018914 @default.
• W2022745065 hasConcept C185592680 @default.
• W2022745065 hasConcept C2776986829 @default.
• W2022745065 hasConcept C2777504413 @default.
• W2022745065 hasConcept C2779281246 @default.
• W2022745065 hasConcept C2779422922 @default.
• W2022745065 hasConcept C2779564779 @default.
• W2022745065 hasConcept C2781283050 @default.
• W2022745065 hasConcept C49039625 @default.

• next