Matches in SemOpenAlex for { <https://semopenalex.org/work/W2022752974> ?p ?o ?g. }
- W2022752974 endingPage "3417" @default.
- W2022752974 startingPage "3412" @default.
- W2022752974 abstract "A new visualizing method was developed for monitoring protein-protein (P-P) interactions in live mammalian cells. P-P interactions are visualized by directing localization of a bait protein to endosomes. This method is sufficiently robust to analyze signal-dependent P-P interactions such as calcium-dependent protein interactions. We visualized interactions between activated calmodulin and calmodulin-binding proteins, and observed oscillatory interactions via time-lapse imaging. In addition, this new method can simultaneously monitor multiple P-P interactions in a single live cell, which allows comparison of interactions between several prey proteins and a single bait protein. We observed that CaMKK1 and CaMKIIalpha bind calmodulin with distinct binding affinities in live cell, which indicates that calcium signaling is fine-tuned by distinct activation patterns of CaM kinases. This method will enable investigation of cellular processes based on dynamic P-P interactions." @default.
- W2022752974 created "2016-06-24" @default.
- W2022752974 creator A5014524055 @default.
- W2022752974 creator A5039373480 @default.
- W2022752974 creator A5040839751 @default.
- W2022752974 creator A5054681353 @default.
- W2022752974 creator A5089863464 @default.
- W2022752974 date "2010-02-03" @default.
- W2022752974 modified "2023-09-26" @default.
- W2022752974 title "Visualizing dynamic interaction between calmodulin and calmodulin-related kinases via a monitoring method in live mammalian cells" @default.
- W2022752974 cites W1485297825 @default.
- W2022752974 cites W1595083713 @default.
- W2022752974 cites W1599277155 @default.
- W2022752974 cites W1603731520 @default.
- W2022752974 cites W1651058823 @default.
- W2022752974 cites W1976429096 @default.
- W2022752974 cites W1987005832 @default.
- W2022752974 cites W1997570875 @default.
- W2022752974 cites W1998678953 @default.
- W2022752974 cites W2007513923 @default.
- W2022752974 cites W2024398910 @default.
- W2022752974 cites W2029565291 @default.
- W2022752974 cites W2033844584 @default.
- W2022752974 cites W2034424952 @default.
- W2022752974 cites W2040004060 @default.
- W2022752974 cites W2043409309 @default.
- W2022752974 cites W2045194954 @default.
- W2022752974 cites W2052366943 @default.
- W2022752974 cites W2075726466 @default.
- W2022752974 cites W2081897739 @default.
- W2022752974 cites W2084344997 @default.
- W2022752974 cites W2085707729 @default.
- W2022752974 cites W2097302886 @default.
- W2022752974 cites W2099199220 @default.
- W2022752974 cites W2101181377 @default.
- W2022752974 cites W2115736681 @default.
- W2022752974 cites W2137530206 @default.
- W2022752974 cites W2145330934 @default.
- W2022752974 cites W2153258572 @default.
- W2022752974 cites W2165104370 @default.
- W2022752974 cites W2182636797 @default.
- W2022752974 doi "https://doi.org/10.1073/pnas.0911262107" @default.
- W2022752974 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2816199" @default.
- W2022752974 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/20133723" @default.
- W2022752974 hasPublicationYear "2010" @default.
- W2022752974 type Work @default.
- W2022752974 sameAs 2022752974 @default.
- W2022752974 citedByCount "18" @default.
- W2022752974 countsByYear W20227529742012 @default.
- W2022752974 countsByYear W20227529742013 @default.
- W2022752974 countsByYear W20227529742014 @default.
- W2022752974 countsByYear W20227529742016 @default.
- W2022752974 countsByYear W20227529742018 @default.
- W2022752974 countsByYear W20227529742022 @default.
- W2022752974 countsByYear W20227529742023 @default.
- W2022752974 crossrefType "journal-article" @default.
- W2022752974 hasAuthorship W2022752974A5014524055 @default.
- W2022752974 hasAuthorship W2022752974A5039373480 @default.
- W2022752974 hasAuthorship W2022752974A5040839751 @default.
- W2022752974 hasAuthorship W2022752974A5054681353 @default.
- W2022752974 hasAuthorship W2022752974A5089863464 @default.
- W2022752974 hasBestOaLocation W20227529741 @default.
- W2022752974 hasConcept C102747710 @default.
- W2022752974 hasConcept C11804247 @default.
- W2022752974 hasConcept C12554922 @default.
- W2022752974 hasConcept C1491633281 @default.
- W2022752974 hasConcept C15526883 @default.
- W2022752974 hasConcept C181199279 @default.
- W2022752974 hasConcept C184235292 @default.
- W2022752974 hasConcept C185592680 @default.
- W2022752974 hasConcept C201571599 @default.
- W2022752974 hasConcept C2775847163 @default.
- W2022752974 hasConcept C29688787 @default.
- W2022752974 hasConcept C51639874 @default.
- W2022752974 hasConcept C55493867 @default.
- W2022752974 hasConcept C62478195 @default.
- W2022752974 hasConcept C79879829 @default.
- W2022752974 hasConcept C86803240 @default.
- W2022752974 hasConcept C95444343 @default.
- W2022752974 hasConceptScore W2022752974C102747710 @default.
- W2022752974 hasConceptScore W2022752974C11804247 @default.
- W2022752974 hasConceptScore W2022752974C12554922 @default.
- W2022752974 hasConceptScore W2022752974C1491633281 @default.
- W2022752974 hasConceptScore W2022752974C15526883 @default.
- W2022752974 hasConceptScore W2022752974C181199279 @default.
- W2022752974 hasConceptScore W2022752974C184235292 @default.
- W2022752974 hasConceptScore W2022752974C185592680 @default.
- W2022752974 hasConceptScore W2022752974C201571599 @default.
- W2022752974 hasConceptScore W2022752974C2775847163 @default.
- W2022752974 hasConceptScore W2022752974C29688787 @default.
- W2022752974 hasConceptScore W2022752974C51639874 @default.
- W2022752974 hasConceptScore W2022752974C55493867 @default.
- W2022752974 hasConceptScore W2022752974C62478195 @default.
- W2022752974 hasConceptScore W2022752974C79879829 @default.
- W2022752974 hasConceptScore W2022752974C86803240 @default.
- W2022752974 hasConceptScore W2022752974C95444343 @default.
- W2022752974 hasIssue "8" @default.
- W2022752974 hasLocation W20227529741 @default.