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- W2022753850 abstract "BCL2 and MYC are oncogenes often deregulated in lymphomas. Concurrent IGH-BCL2 and MYC translocations result in a highly aggressive behavior of these tumors. Both primary breast lymphoma and lymphoma with concurrent BCL2-IGH and MYC translocations are rare and are primarily seen in adult patients. As a result of limited clinician experience and the condition's rarity, it poses a great challenge to pediatric pathologists and oncologists in terms of making an accurate diagnosis and choosing better treatment regimens. In this article, we report a case of an adolescent patient who presented with high-grade breast lymphoma with concurrent BCL2-IGH and MYC-IGL translocations, and we review the clinical, pathological, and genetic features; management strategies; and outcomes associated with this unusual neoplasm." @default.
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- W2022753850 date "2011-09-01" @default.
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- W2022753850 title "Primary High-Grade B-Cell Lymphoma of the Breast with Concurrent IGH-BCL2 and MYC-IGL Translocations in an Adolescent Patient" @default.
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- W2022753850 doi "https://doi.org/10.2350/10-10-0927-cr.1" @default.
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