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- W2022757759 abstract "The antifertility activity of chlormadinone and norethindrone, administered preovulatory, postovulatory or continuously was examined in the rabbit. Chlormadinone was considerably more potent than norethindrone by preovulatory treatment. With each compound a specific dose was found to be active by preovulatory treatment, but inactive when the dose was given continuously. Postovulatory treatment revealed a striking separation of action in that norethindrone inhibited fertility, while chlormadinone was totally inactive. When chlormadinone was given preovulatory, and norethindrone postovulatory, at doses that alone were inactive, a significant inhibition of fertility was observed. Sequential administration of these progestins appeared to enhance specificity, and broaden the total spectrum of antifertility influence." @default.
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- W2022757759 title "Complimentary, sequential antifertility effects of chlormadinone and norethindrone in the rabbit: Implications in progestin only fertility control" @default.
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- W2022757759 doi "https://doi.org/10.1016/s0010-7824(75)80022-9" @default.
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