FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2022759227> ?p ?o ?g. }

• W2022759227 endingPage "872" @default.
• W2022759227 startingPage "866" @default.
• W2022759227 abstract "There is an association between depression and chronic pain, and some antidepressants exert antinociceptive effects in humans and laboratory animals. We examined the effects of fluvoxamine, a selective serotonin reuptake inhibitor, on mechanical allodynia and its mechanism of action in the mouse chronic pain model, which was prepared by partially ligating the sciatic nerve. The antiallodynic effect was measured using the von Frey test. Fluvoxamine produced antiallodynic effects following both systemic and intrathecal administration. In 5-hydroxytryptamine (5-HT)-depleted mice, prepared by intracerebroventricular injection of 5,7-dihyroxytryptamine, the fluvoxamine-induced antiallodynic effect was significantly attenuated. The antiallodynic effects of systemic fluvoxamine were also reduced by both systemic and intrathecal administration of ketanserin, a 5-HT2A/2C receptor antagonist. In addition, fluvoxamine also induced antinociceptive effect in the acute paw pressure test, and this effect was antagonized by the 5-HT3 receptor antagonist granisetron. These results indicate that fluvoxamine exerts its antiallodynic effects on neuropathic pain via descending 5-HT fibers and spinal 5-HT2A or 5-HT2C receptors, and the antinociception on acute mechanical pain via 5-HT3 receptors." @default.
• W2022759227 created "2016-06-24" @default.
• W2022759227 creator A5010576233 @default.
• W2022759227 creator A5056231988 @default.
• W2022759227 creator A5087706077 @default.
• W2022759227 creator A5091092306 @default.
• W2022759227 date "2006-09-01" @default.
• W2022759227 modified "2023-10-14" @default.
• W2022759227 title "Fluvoxamine, a selective serotonin reuptake inhibitor, exerts its antiallodynic effects on neuropathic pain in mice via 5-HT2A/2C receptors" @default.
• W2022759227 cites W1902452403 @default.
• W2022759227 cites W1967786275 @default.
• W2022759227 cites W1969040411 @default.
• W2022759227 cites W1969167720 @default.
• W2022759227 cites W1969328867 @default.
• W2022759227 cites W1972691689 @default.
• W2022759227 cites W1972856190 @default.
• W2022759227 cites W1985648594 @default.
• W2022759227 cites W1988677318 @default.
• W2022759227 cites W1991216581 @default.
• W2022759227 cites W2006855860 @default.
• W2022759227 cites W2020820202 @default.
• W2022759227 cites W2024952531 @default.
• W2022759227 cites W2025964232 @default.
• W2022759227 cites W2028243509 @default.
• W2022759227 cites W2028573801 @default.
• W2022759227 cites W2032132035 @default.
• W2022759227 cites W2034102455 @default.
• W2022759227 cites W2040540166 @default.
• W2022759227 cites W2041498217 @default.
• W2022759227 cites W2044648344 @default.
• W2022759227 cites W2045108246 @default.
• W2022759227 cites W2047630289 @default.
• W2022759227 cites W2052315307 @default.
• W2022759227 cites W2057019451 @default.
• W2022759227 cites W2057021202 @default.
• W2022759227 cites W2057495371 @default.
• W2022759227 cites W2067924690 @default.
• W2022759227 cites W2069466951 @default.
• W2022759227 cites W2071159528 @default.
• W2022759227 cites W2080070699 @default.
• W2022759227 cites W2094569992 @default.
• W2022759227 cites W2094823797 @default.
• W2022759227 cites W2102023851 @default.
• W2022759227 cites W2103351070 @default.
• W2022759227 cites W2130620287 @default.
• W2022759227 cites W2142667771 @default.
• W2022759227 cites W2172201406 @default.
• W2022759227 cites W2189649144 @default.
• W2022759227 cites W2254815352 @default.
• W2022759227 cites W2255643175 @default.
• W2022759227 doi "https://doi.org/10.1016/j.neuropharm.2006.05.031" @default.
• W2022759227 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/16846619" @default.
• W2022759227 hasPublicationYear "2006" @default.
• W2022759227 type Work @default.
• W2022759227 sameAs 2022759227 @default.
• W2022759227 citedByCount "50" @default.
• W2022759227 countsByYear W20227592272012 @default.
• W2022759227 countsByYear W20227592272013 @default.
• W2022759227 countsByYear W20227592272014 @default.
• W2022759227 countsByYear W20227592272015 @default.
• W2022759227 countsByYear W20227592272017 @default.
• W2022759227 countsByYear W20227592272018 @default.
• W2022759227 countsByYear W20227592272019 @default.
• W2022759227 countsByYear W20227592272020 @default.
• W2022759227 countsByYear W20227592272021 @default.
• W2022759227 countsByYear W20227592272022 @default.
• W2022759227 crossrefType "journal-article" @default.
• W2022759227 hasAuthorship W2022759227A5010576233 @default.
• W2022759227 hasAuthorship W2022759227A5056231988 @default.
• W2022759227 hasAuthorship W2022759227A5087706077 @default.
• W2022759227 hasAuthorship W2022759227A5091092306 @default.
• W2022759227 hasConcept C126322002 @default.
• W2022759227 hasConcept C15490471 @default.
• W2022759227 hasConcept C170493617 @default.
• W2022759227 hasConcept C2775864247 @default.
• W2022759227 hasConcept C2776134451 @default.
• W2022759227 hasConcept C2776885963 @default.
• W2022759227 hasConcept C2777107010 @default.
• W2022759227 hasConcept C2777785214 @default.
• W2022759227 hasConcept C2777883359 @default.
• W2022759227 hasConcept C2778122271 @default.
• W2022759227 hasConcept C2779245659 @default.
• W2022759227 hasConcept C2779910183 @default.
• W2022759227 hasConcept C2780092697 @default.
• W2022759227 hasConcept C31487548 @default.
• W2022759227 hasConcept C53910766 @default.
• W2022759227 hasConcept C71924100 @default.
• W2022759227 hasConcept C98274493 @default.
• W2022759227 hasConceptScore W2022759227C126322002 @default.
• W2022759227 hasConceptScore W2022759227C15490471 @default.
• W2022759227 hasConceptScore W2022759227C170493617 @default.
• W2022759227 hasConceptScore W2022759227C2775864247 @default.
• W2022759227 hasConceptScore W2022759227C2776134451 @default.
• W2022759227 hasConceptScore W2022759227C2776885963 @default.
• W2022759227 hasConceptScore W2022759227C2777107010 @default.
• W2022759227 hasConceptScore W2022759227C2777785214 @default.
• W2022759227 hasConceptScore W2022759227C2777883359 @default.
• W2022759227 hasConceptScore W2022759227C2778122271 @default.

• next