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- W2022777984 abstract "EDTA plasma samples from 19 newborn infants were analysed with respect to growth hormona(HGH) calcitonin(CT) and plasma calcium. Ten IDM and nine controls were studied. Blood was obtained from the umbilical artery(IDM) every third hour from birth up to 30 hours of age, and from a peripheral vein (controls) respectively at 0, 3, 6, 12 and 24-29 hours of age. Plasma calcium conc. decreased after birth in both groups, but more markedly in the IDM. The conc. of HGH increased in both groups, the increase being most pronounced in the IDM. At 3-6 hours after birth the mean in the IDM was 46 mU/l and 18 mU/l in the controls. The variations in the HGH conc. were more marked in the IDM. Up to 24 hours of age 6 of 9 controls had maximum values below 50 mU/l, whereas 9 of 10 IDM had 2-7 values above 50 mU/l. A significant negative correlation between HGH and plasma calcium was found in both groups. The CT measurements are in progress. Previous results show marked increase in the CT conc. in both groups after birth. The results support the hypothesis given previously (Bergman, 1974) i.e., that there will be a pronounced decrease in plasma calcium conc. if there is an increase of plasma HGH conc. leading to high bone turnover at a time, when the conc. of CT is high. This may indicate that the conc. of HGH is an important parameter in the development of early neonatal hypocalcemia." @default.
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- W2022777984 date "1976-10-01" @default.
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- W2022777984 title "174: Growth hormone and calcitonin: Possible relation to the exaggerated decrease in plasma calcium in infants of diabetic mothers (IDM) after birth" @default.
- W2022777984 doi "https://doi.org/10.1203/00006450-197610000-00165" @default.
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