Matches in SemOpenAlex for { <https://semopenalex.org/work/W2022779726> ?p ?o ?g. }
Showing items 1 to 84 of
84
with 100 items per page.
- W2022779726 endingPage "131" @default.
- W2022779726 startingPage "127" @default.
- W2022779726 abstract "Mononuclear leukocytes (MNL) were isolated from human blood by Ficoll-Hypaque. These cells were further separated into lymphocyte (L) and monocyte (M) enriched fractions. L contained 99% lymphocytes and M contained 74% monocytes, a threefold enrichment over MNL. Specific binding to somatostatin, glucagon, and insulin was measured in the three fractions. Binding of all three hormones in the M fraction was increased by a factor of 3 compared with MNL and was linear with cell number. Binding of glucagon and insulin to the L fraction was very low while, in contrast, somatostatin binding was substantial and linear with lymphocyte number. Autoradiography confirmed the binding of glucagon to monocytes and of somatostatin to both monocytes and lymphocytes. Somatostatin is the first of the peptide hormones shown to bind to both types of circulating mononuclear cells, perhaps complicating quantification of somatostatin binding in disease states in which differential alteration of binding of lymphocytes or monocytes might occur." @default.
- W2022779726 created "2016-06-24" @default.
- W2022779726 creator A5003422547 @default.
- W2022779726 creator A5010657812 @default.
- W2022779726 creator A5039015296 @default.
- W2022779726 creator A5068119256 @default.
- W2022779726 creator A5078775336 @default.
- W2022779726 creator A5083547706 @default.
- W2022779726 date "1981-02-01" @default.
- W2022779726 modified "2023-10-15" @default.
- W2022779726 title "Identification of Human Mononuclear Leukocytes Bearing Receptors for Somatostatin and Glucagon" @default.
- W2022779726 doi "https://doi.org/10.2337/diab.30.2.127" @default.
- W2022779726 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/6110596" @default.
- W2022779726 hasPublicationYear "1981" @default.
- W2022779726 type Work @default.
- W2022779726 sameAs 2022779726 @default.
- W2022779726 citedByCount "105" @default.
- W2022779726 countsByYear W20227797262018 @default.
- W2022779726 countsByYear W20227797262021 @default.
- W2022779726 crossrefType "journal-article" @default.
- W2022779726 hasAuthorship W2022779726A5003422547 @default.
- W2022779726 hasAuthorship W2022779726A5010657812 @default.
- W2022779726 hasAuthorship W2022779726A5039015296 @default.
- W2022779726 hasAuthorship W2022779726A5068119256 @default.
- W2022779726 hasAuthorship W2022779726A5078775336 @default.
- W2022779726 hasAuthorship W2022779726A5083547706 @default.
- W2022779726 hasConcept C126322002 @default.
- W2022779726 hasConcept C134018914 @default.
- W2022779726 hasConcept C137061746 @default.
- W2022779726 hasConcept C152091265 @default.
- W2022779726 hasConcept C170493617 @default.
- W2022779726 hasConcept C185592680 @default.
- W2022779726 hasConcept C202751555 @default.
- W2022779726 hasConcept C2776297358 @default.
- W2022779726 hasConcept C2777761686 @default.
- W2022779726 hasConcept C2778563252 @default.
- W2022779726 hasConcept C2779306644 @default.
- W2022779726 hasConcept C2781184567 @default.
- W2022779726 hasConcept C55493867 @default.
- W2022779726 hasConcept C56191518 @default.
- W2022779726 hasConcept C71315377 @default.
- W2022779726 hasConcept C71924100 @default.
- W2022779726 hasConcept C80115893 @default.
- W2022779726 hasConcept C86803240 @default.
- W2022779726 hasConceptScore W2022779726C126322002 @default.
- W2022779726 hasConceptScore W2022779726C134018914 @default.
- W2022779726 hasConceptScore W2022779726C137061746 @default.
- W2022779726 hasConceptScore W2022779726C152091265 @default.
- W2022779726 hasConceptScore W2022779726C170493617 @default.
- W2022779726 hasConceptScore W2022779726C185592680 @default.
- W2022779726 hasConceptScore W2022779726C202751555 @default.
- W2022779726 hasConceptScore W2022779726C2776297358 @default.
- W2022779726 hasConceptScore W2022779726C2777761686 @default.
- W2022779726 hasConceptScore W2022779726C2778563252 @default.
- W2022779726 hasConceptScore W2022779726C2779306644 @default.
- W2022779726 hasConceptScore W2022779726C2781184567 @default.
- W2022779726 hasConceptScore W2022779726C55493867 @default.
- W2022779726 hasConceptScore W2022779726C56191518 @default.
- W2022779726 hasConceptScore W2022779726C71315377 @default.
- W2022779726 hasConceptScore W2022779726C71924100 @default.
- W2022779726 hasConceptScore W2022779726C80115893 @default.
- W2022779726 hasConceptScore W2022779726C86803240 @default.
- W2022779726 hasIssue "2" @default.
- W2022779726 hasLocation W20227797261 @default.
- W2022779726 hasLocation W20227797262 @default.
- W2022779726 hasOpenAccess W2022779726 @default.
- W2022779726 hasPrimaryLocation W20227797261 @default.
- W2022779726 hasRelatedWork W1568509230 @default.
- W2022779726 hasRelatedWork W1741250325 @default.
- W2022779726 hasRelatedWork W1980224375 @default.
- W2022779726 hasRelatedWork W1993878025 @default.
- W2022779726 hasRelatedWork W2008562659 @default.
- W2022779726 hasRelatedWork W2101584318 @default.
- W2022779726 hasRelatedWork W2134332610 @default.
- W2022779726 hasRelatedWork W2140741951 @default.
- W2022779726 hasRelatedWork W2622006895 @default.
- W2022779726 hasRelatedWork W3216403534 @default.
- W2022779726 hasVolume "30" @default.
- W2022779726 isParatext "false" @default.
- W2022779726 isRetracted "false" @default.
- W2022779726 magId "2022779726" @default.
- W2022779726 workType "article" @default.