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- W2022783248 abstract "In view of the known role of Ca2+ in the paroxysmal depolarization shifts of epileptic neurones, the possibility arises that certain Ca2+ entry blockers possess antiepileptic activity. The only drug of the class which readily passes the blood-brain barrier is flunarizine. This is effective in experimental models of epilepsy and produced significant seizure reduction in two therapeutic trials in therapy-resistant patients. It has few and mild side effects at therapeutic blood levels." @default.
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- W2022783248 date "1986-01-01" @default.
- W2022783248 modified "2023-09-26" @default.
- W2022783248 title "Add-On Therapy in Epilepsy with Calcium Entry Blockers" @default.
- W2022783248 doi "https://doi.org/10.1159/000116104" @default.
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