Matches in SemOpenAlex for { <https://semopenalex.org/work/W2022783462> ?p ?o ?g. }
- W2022783462 endingPage "768" @default.
- W2022783462 startingPage "757" @default.
- W2022783462 abstract "Coenzyme Q10 (Q10), carotenoids, tocopherols, and retinol are the major circulating lipid-phase micronutrients (LPM) known to help mitigate oxidative damage and prevent chronic diseases. However, the functions of these compounds in newborns are little understood. This is due, in part, to the paucity of studies reporting their concentrations in this population. We measured Q10, carotenoids, tocopherols, and retinol in cord plasma from 100 multiethnic subjects living in Hawaii using HPLC with diode array and electrochemical detection. Appropriate internal standards were used including, for the first time, custom designed oxidized (UN10) and reduced (UL10) Q10 analogues. These compounds reflected the oxidation of UL10 to UN10 that occurred during sample processing and analysis and thus permitted accurate adjustments of natively circulating Q10 levels. All LPM measured were much lower in cord than in peripheral plasma. Cord plasma levels of total carotenoids, tocopherols, and retinol were approximately 10-fold, 3- to 5-fold and 1.5- to 3-fold lower than those in children or women. Cord plasma levels of total Q10 (TQ10; median, 113 ng/mL) were approximately 2-fold or 7- to 9-fold lower than peripheral plasma levels of neonates or children and adults, respectively. In contrast, the UN10/TQ10 ratio was substantially higher in cord (24%) than in peripheral plasma of children (3-4%) or adults (9%). Among the 5 ethnic groups in our cohort, no differences were observed in the levels of UN10, UL10, or TQ10. However, significant differences in many of the LPM were observed between ethnicities. More research is needed to explain these phenomena." @default.
- W2022783462 created "2016-06-24" @default.
- W2022783462 creator A5019126987 @default.
- W2022783462 creator A5031330914 @default.
- W2022783462 creator A5039239655 @default.
- W2022783462 creator A5039526783 @default.
- W2022783462 creator A5070851218 @default.
- W2022783462 creator A5072706566 @default.
- W2022783462 creator A5077982482 @default.
- W2022783462 creator A5088224288 @default.
- W2022783462 date "2013-08-02" @default.
- W2022783462 modified "2023-10-03" @default.
- W2022783462 title "Coenzyme Q10, carotenoid, tocopherol, and retinol levels in cord plasma from multiethnic subjects in Hawaii" @default.
- W2022783462 cites W1526082129 @default.
- W2022783462 cites W1536773986 @default.
- W2022783462 cites W1574441056 @default.
- W2022783462 cites W1841957993 @default.
- W2022783462 cites W1941294128 @default.
- W2022783462 cites W1964874366 @default.
- W2022783462 cites W1964891568 @default.
- W2022783462 cites W1971748463 @default.
- W2022783462 cites W1976069407 @default.
- W2022783462 cites W1979121405 @default.
- W2022783462 cites W1980232183 @default.
- W2022783462 cites W1980265413 @default.
- W2022783462 cites W1980728705 @default.
- W2022783462 cites W1980945922 @default.
- W2022783462 cites W1981776442 @default.
- W2022783462 cites W1984119010 @default.
- W2022783462 cites W1985665857 @default.
- W2022783462 cites W1989795013 @default.
- W2022783462 cites W1992822666 @default.
- W2022783462 cites W1993308019 @default.
- W2022783462 cites W1997537895 @default.
- W2022783462 cites W2002532393 @default.
- W2022783462 cites W2006483680 @default.
- W2022783462 cites W2010734488 @default.
- W2022783462 cites W2015189666 @default.
- W2022783462 cites W2025794221 @default.
- W2022783462 cites W2028764252 @default.
- W2022783462 cites W2033819095 @default.
- W2022783462 cites W2034099563 @default.
- W2022783462 cites W2034277702 @default.
- W2022783462 cites W2035064090 @default.
- W2022783462 cites W2040106968 @default.
- W2022783462 cites W2041749596 @default.
- W2022783462 cites W2041754877 @default.
- W2022783462 cites W2042021152 @default.
- W2022783462 cites W2042632977 @default.
- W2022783462 cites W2043686330 @default.
- W2022783462 cites W2043948984 @default.
- W2022783462 cites W2047846803 @default.
- W2022783462 cites W2047950591 @default.
- W2022783462 cites W2055516334 @default.
- W2022783462 cites W2056850217 @default.
- W2022783462 cites W2059516260 @default.
- W2022783462 cites W2060363769 @default.
- W2022783462 cites W2061352029 @default.
- W2022783462 cites W2062955140 @default.
- W2022783462 cites W2066375606 @default.
- W2022783462 cites W2066504626 @default.
- W2022783462 cites W2068902736 @default.
- W2022783462 cites W2077187692 @default.
- W2022783462 cites W2077927747 @default.
- W2022783462 cites W2082648668 @default.
- W2022783462 cites W2083259478 @default.
- W2022783462 cites W2088315471 @default.
- W2022783462 cites W2090857330 @default.
- W2022783462 cites W2094567706 @default.
- W2022783462 cites W2094858431 @default.
- W2022783462 cites W2095014707 @default.
- W2022783462 cites W2096535920 @default.
- W2022783462 cites W2101407647 @default.
- W2022783462 cites W2101564653 @default.
- W2022783462 cites W2106840587 @default.
- W2022783462 cites W2106936194 @default.
- W2022783462 cites W2117362502 @default.
- W2022783462 cites W2119296764 @default.
- W2022783462 cites W2119862041 @default.
- W2022783462 cites W2126705302 @default.
- W2022783462 cites W2135734690 @default.
- W2022783462 cites W2137672734 @default.
- W2022783462 cites W2138961575 @default.
- W2022783462 cites W2150874686 @default.
- W2022783462 cites W2153636008 @default.
- W2022783462 cites W2155441061 @default.
- W2022783462 cites W2158842080 @default.
- W2022783462 cites W2160130445 @default.
- W2022783462 cites W2160835393 @default.
- W2022783462 cites W2161502945 @default.
- W2022783462 cites W2169041033 @default.
- W2022783462 cites W2169723026 @default.
- W2022783462 cites W2169831621 @default.
- W2022783462 cites W2171269607 @default.
- W2022783462 cites W2247036623 @default.
- W2022783462 cites W2336692225 @default.
- W2022783462 cites W60263660 @default.
- W2022783462 doi "https://doi.org/10.3109/10715762.2013.822495" @default.