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- W2022785992 abstract "A biomarker for phenolic carcinogen exposure, 8-(4''-hydroxyphenyl)-2'-deoxyguanosine, has been found to undergo oxidative coupling in the presence of Na2IrCl6 to afford ortho-ortho C-C-coupled polyphenols through the intermediacy of a phenoxyl radical. One can envision using such unique chemistry to oxidatively couple strands of DNA for the generation of new biomaterials. Our results also demonstrate the potential for phenolic adducts of DNA to undergo further oxidation reactions that may contribute to phenol-mediated cytotoxicity and genotoxicity." @default.
- W2022785992 created "2016-06-24" @default.
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- W2022785992 date "2008-04-08" @default.
- W2022785992 modified "2023-10-13" @default.
- W2022785992 title "Oxidation of a Biomarker for Phenol Carcinogen Exposure: Expanding the Redox Chemistry of 2′-Deoxyguanosine" @default.
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- W2022785992 doi "https://doi.org/10.1021/ol8004694" @default.
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