FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2022790832> ?p ?o ?g. }

• W2022790832 endingPage "1123" @default.
• W2022790832 startingPage "1113" @default.
• W2022790832 abstract "There are indications that a close HLA match may not be necessary when human umbilical cord blood (HUCB) is used to effect a hematopoietic transplant. This was first suggested in 1972 and was further supported by the ability of HUCB to produce mouse survival following lethal irradiation. In China multiple units of HLA unmatched HUCB was utilized successfully in children to effect transplants. A recent publication indicated that newborn rodent blood cells can engraft in adult mice across the non-H-2 [corrected] antigens. Furthermore, there recently have been successful transplants with 3 antigens mismatched HUCB. In this study HUCB was stored in polyolefin blood bank bags at 4 degrees C. The storage was similar to that used in routine blood banking. Clonogenic assays were performed at Day 1 and 21 utilizing various growth factors. Replating efficiency was determined on colonies obtained from cord blood that was stored (non-frozen) for 21 days. The functional ability of day 21 old HUCB was determined by its ability to produce survival of lethally irradiated mice. It was found that approximately two-thirds (62.5%) of single primary blast cell colonies in day 21 stored HUCB could generate various types of secondary colonies. In some instances the secondary colonies were counted as high as 42 total mean colonies per single primary colony. These blast cell colonies (CFU-BL) were able to form single and multi lineage colonies composed of virtually every hematopoietic cell types. Animal survival studies were utilized in an effort to determine possible functional ability and were successful in producing fifty-day survival in 54% of lethally irradiated SJL/J mice and 100% ALB/C mice. This study holds the potential of making HUCB available for purposes of marrow transplantation to all who need it. It could further remove most of the moral and ethical issues related to HUCB, reduce to a fraction the cost in providing stem cells for marrow transplantation and potentially allow HUCB to be handled by existing blood banks." @default.
• W2022790832 created "2016-06-24" @default.
• W2022790832 creator A5022657145 @default.
• W2022790832 creator A5028367011 @default.
• W2022790832 date "1997-08-01" @default.
• W2022790832 modified "2023-09-26" @default.
• W2022790832 title "Potential for clinical use of viable pluripotent progenitor cells in blood bank stored human umbilical cord blood" @default.
• W2022790832 cites W1482517818 @default.
• W2022790832 cites W1592018386 @default.
• W2022790832 cites W1597936383 @default.
• W2022790832 cites W1608125173 @default.
• W2022790832 cites W1838336174 @default.
• W2022790832 cites W1994666296 @default.
• W2022790832 cites W2004543423 @default.
• W2022790832 cites W2034023225 @default.
• W2022790832 cites W2040941274 @default.
• W2022790832 cites W2074652905 @default.
• W2022790832 cites W2076364447 @default.
• W2022790832 cites W2092234690 @default.
• W2022790832 cites W2259098203 @default.
• W2022790832 cites W2333162405 @default.
• W2022790832 cites W2341421479 @default.
• W2022790832 cites W2399724929 @default.
• W2022790832 cites W2414854471 @default.
• W2022790832 cites W36714059 @default.
• W2022790832 cites W597759872 @default.
• W2022790832 doi "https://doi.org/10.1016/s0024-3205(97)00645-0" @default.
• W2022790832 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/9315503" @default.
• W2022790832 hasPublicationYear "1997" @default.
• W2022790832 type Work @default.
• W2022790832 sameAs 2022790832 @default.
• W2022790832 citedByCount "3" @default.
• W2022790832 crossrefType "journal-article" @default.
• W2022790832 hasAuthorship W2022790832A5022657145 @default.
• W2022790832 hasAuthorship W2022790832A5028367011 @default.
• W2022790832 hasConcept C109159458 @default.
• W2022790832 hasConcept C117262875 @default.
• W2022790832 hasConcept C1491633281 @default.
• W2022790832 hasConcept C16685009 @default.
• W2022790832 hasConcept C201750760 @default.
• W2022790832 hasConcept C203014093 @default.
• W2022790832 hasConcept C2776955114 @default.
• W2022790832 hasConcept C2779979121 @default.
• W2022790832 hasConcept C2780914630 @default.
• W2022790832 hasConcept C28328180 @default.
• W2022790832 hasConcept C54355233 @default.
• W2022790832 hasConcept C71924100 @default.
• W2022790832 hasConcept C86803240 @default.
• W2022790832 hasConcept C95444343 @default.
• W2022790832 hasConceptScore W2022790832C109159458 @default.
• W2022790832 hasConceptScore W2022790832C117262875 @default.
• W2022790832 hasConceptScore W2022790832C1491633281 @default.
• W2022790832 hasConceptScore W2022790832C16685009 @default.
• W2022790832 hasConceptScore W2022790832C201750760 @default.
• W2022790832 hasConceptScore W2022790832C203014093 @default.
• W2022790832 hasConceptScore W2022790832C2776955114 @default.
• W2022790832 hasConceptScore W2022790832C2779979121 @default.
• W2022790832 hasConceptScore W2022790832C2780914630 @default.
• W2022790832 hasConceptScore W2022790832C28328180 @default.
• W2022790832 hasConceptScore W2022790832C54355233 @default.
• W2022790832 hasConceptScore W2022790832C71924100 @default.
• W2022790832 hasConceptScore W2022790832C86803240 @default.
• W2022790832 hasConceptScore W2022790832C95444343 @default.
• W2022790832 hasIssue "12" @default.
• W2022790832 hasLocation W20227908321 @default.
• W2022790832 hasLocation W20227908322 @default.
• W2022790832 hasOpenAccess W2022790832 @default.
• W2022790832 hasPrimaryLocation W20227908321 @default.
• W2022790832 hasRelatedWork W1996222681 @default.
• W2022790832 hasRelatedWork W2039567834 @default.
• W2022790832 hasRelatedWork W2062256187 @default.
• W2022790832 hasRelatedWork W2315198467 @default.
• W2022790832 hasRelatedWork W2397715141 @default.
• W2022790832 hasRelatedWork W2409893191 @default.
• W2022790832 hasRelatedWork W2416513233 @default.
• W2022790832 hasRelatedWork W2416969871 @default.
• W2022790832 hasRelatedWork W2468610105 @default.
• W2022790832 hasRelatedWork W4246977199 @default.
• W2022790832 hasVolume "61" @default.
• W2022790832 isParatext "false" @default.
• W2022790832 isRetracted "false" @default.
• W2022790832 magId "2022790832" @default.
• W2022790832 workType "article" @default.