Matches in SemOpenAlex for { <https://semopenalex.org/work/W2022790853> ?p ?o ?g. }
- W2022790853 endingPage "3673" @default.
- W2022790853 startingPage "3673" @default.
- W2022790853 abstract "purpose. To examine phototransduction using the a-wave and other aspects of retinal function with the intraretinal b- and c-waves at different stages of an inherited photoreceptor degeneration in Abyssinian cats. methods. Vitreal and intraretinal ERGs were recorded from eight dark-adapted, anesthetized Abyssinian cats. Brief bright flashes were used to elicit vitreal a- and b-waves. Longer, weaker flashes were used to elicit intraretinal b- and c-waves. Stages 1 through 4 of the disease were characterized ophthalmoscopically. Parameters of the Lamb and Pugh a-wave model (a max, A, and t eff) for the Abyssinian cats were compared with those for normal cats. Light microscopy was used to count photoreceptor nuclei. results. The maximum a-wave amplitude, a max, was significantly smaller in stage 1, and continued to decrease (stage 1: 50% of normal, stage 2: 28%, stage 3: 27%; and stage 4: unrecordable). There was a small, but not significant, decrease in the amplification constant A from 0.24 ± 0.11 s−2 in normal cats to 0.16 ± 0.08 s−2 in Abyssinian cats. The intraretinal b- and c-wave amplitudes decreased most dramatically during the early stage of the disease. Affected animals had fewer photoreceptors than unaffected Abyssinians or control animals. The number of photoreceptors declined most rapidly in the inferior periphery. conclusions. The amplitudes of all ERG components were already reduced significantly by stage 1 and progressively declined. The lack of major changes in a-wave model parameters indicates that the degeneration is probably not due to a mutation in transduction proteins. Losses of photoreceptor function were larger than losses of photoreceptor nuclei." @default.
- W2022790853 created "2016-06-24" @default.
- W2022790853 creator A5006553700 @default.
- W2022790853 creator A5009408620 @default.
- W2022790853 creator A5013314341 @default.
- W2022790853 creator A5028888293 @default.
- W2022790853 creator A5032977759 @default.
- W2022790853 creator A5040763271 @default.
- W2022790853 date "2006-08-01" @default.
- W2022790853 modified "2023-10-10" @default.
- W2022790853 title "The Electroretinogram Components in Abyssinian Cats with Hereditary Retinal Degeneration" @default.
- W2022790853 cites W1543214154 @default.
- W2022790853 cites W1560301419 @default.
- W2022790853 cites W157542615 @default.
- W2022790853 cites W1578554023 @default.
- W2022790853 cites W159190566 @default.
- W2022790853 cites W1599659075 @default.
- W2022790853 cites W17026077 @default.
- W2022790853 cites W175170135 @default.
- W2022790853 cites W1977423618 @default.
- W2022790853 cites W2030433817 @default.
- W2022790853 cites W2035579238 @default.
- W2022790853 cites W2050171989 @default.
- W2022790853 cites W2052947772 @default.
- W2022790853 cites W205588752 @default.
- W2022790853 cites W2056627564 @default.
- W2022790853 cites W2069085811 @default.
- W2022790853 cites W2072088317 @default.
- W2022790853 cites W2109800651 @default.
- W2022790853 cites W2118909794 @default.
- W2022790853 cites W2124613909 @default.
- W2022790853 cites W2128675679 @default.
- W2022790853 cites W2134950472 @default.
- W2022790853 cites W2156788482 @default.
- W2022790853 cites W2344841325 @default.
- W2022790853 cites W2410580465 @default.
- W2022790853 cites W2425652140 @default.
- W2022790853 cites W38574845 @default.
- W2022790853 cites W71001787 @default.
- W2022790853 cites W86405739 @default.
- W2022790853 doi "https://doi.org/10.1167/iovs.05-1283" @default.
- W2022790853 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/16877442" @default.
- W2022790853 hasPublicationYear "2006" @default.
- W2022790853 type Work @default.
- W2022790853 sameAs 2022790853 @default.
- W2022790853 citedByCount "25" @default.
- W2022790853 countsByYear W20227908532012 @default.
- W2022790853 countsByYear W20227908532013 @default.
- W2022790853 countsByYear W20227908532014 @default.
- W2022790853 countsByYear W20227908532016 @default.
- W2022790853 countsByYear W20227908532017 @default.
- W2022790853 countsByYear W20227908532020 @default.
- W2022790853 countsByYear W20227908532022 @default.
- W2022790853 crossrefType "journal-article" @default.
- W2022790853 hasAuthorship W2022790853A5006553700 @default.
- W2022790853 hasAuthorship W2022790853A5009408620 @default.
- W2022790853 hasAuthorship W2022790853A5013314341 @default.
- W2022790853 hasAuthorship W2022790853A5028888293 @default.
- W2022790853 hasAuthorship W2022790853A5032977759 @default.
- W2022790853 hasAuthorship W2022790853A5040763271 @default.
- W2022790853 hasConcept C103796816 @default.
- W2022790853 hasConcept C105702510 @default.
- W2022790853 hasConcept C118487528 @default.
- W2022790853 hasConcept C126322002 @default.
- W2022790853 hasConcept C131667965 @default.
- W2022790853 hasConcept C169760540 @default.
- W2022790853 hasConcept C2777093970 @default.
- W2022790853 hasConcept C2779113765 @default.
- W2022790853 hasConcept C2779354088 @default.
- W2022790853 hasConcept C2779904517 @default.
- W2022790853 hasConcept C2780827179 @default.
- W2022790853 hasConcept C2781040256 @default.
- W2022790853 hasConcept C71924100 @default.
- W2022790853 hasConcept C86803240 @default.
- W2022790853 hasConceptScore W2022790853C103796816 @default.
- W2022790853 hasConceptScore W2022790853C105702510 @default.
- W2022790853 hasConceptScore W2022790853C118487528 @default.
- W2022790853 hasConceptScore W2022790853C126322002 @default.
- W2022790853 hasConceptScore W2022790853C131667965 @default.
- W2022790853 hasConceptScore W2022790853C169760540 @default.
- W2022790853 hasConceptScore W2022790853C2777093970 @default.
- W2022790853 hasConceptScore W2022790853C2779113765 @default.
- W2022790853 hasConceptScore W2022790853C2779354088 @default.
- W2022790853 hasConceptScore W2022790853C2779904517 @default.
- W2022790853 hasConceptScore W2022790853C2780827179 @default.
- W2022790853 hasConceptScore W2022790853C2781040256 @default.
- W2022790853 hasConceptScore W2022790853C71924100 @default.
- W2022790853 hasConceptScore W2022790853C86803240 @default.
- W2022790853 hasIssue "8" @default.
- W2022790853 hasLocation W20227908531 @default.
- W2022790853 hasLocation W20227908532 @default.
- W2022790853 hasOpenAccess W2022790853 @default.
- W2022790853 hasPrimaryLocation W20227908531 @default.
- W2022790853 hasRelatedWork W127476475 @default.
- W2022790853 hasRelatedWork W1997713949 @default.
- W2022790853 hasRelatedWork W2014967917 @default.
- W2022790853 hasRelatedWork W2141327052 @default.
- W2022790853 hasRelatedWork W2156859668 @default.