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- W2022793771 abstract "Replacement of the hydroxy cyclopentanone ring in PGE(2) with chemically more stable heterocyclic rings and substitution of the unsaturated alpha-alkenyl chain with a metabolically more stable phenethyl chain led to the development of potent and selective analogs of PGE(2). Compound 10f showed the highest potency and selectivity for EP(4) the receptor." @default.
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- W2022793771 date "2007-12-01" @default.
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- W2022793771 title "Synthesis and evaluation of novel pyrazolidinone analogs of PGE2 as EP2 and EP4 receptors agonists" @default.
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- W2022793771 doi "https://doi.org/10.1016/j.bmcl.2007.09.074" @default.
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