FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2022793859> ?p ?o ?g. }

• W2022793859 endingPage "52" @default.
• W2022793859 startingPage "41" @default.
• W2022793859 abstract "Primary sclerosing cholangitis is a chronic cholestatic disease characterized by inflammation with fibrosis and obliteration of the intra- and extrahepatic bile ducts. This disease is usually associated with ulcerative colitis. The process of chronic cholestasis eventually leads to biliary cirrhosis. The prevalence of primary sclerosing cholangitis is low in southern Europe but is especially high in Scandinavian countries. The etiopathogenesis is unknown but immune disorders, potential toxic agents or intestinal infections, ischemic injury to the bile ducts, and possibly alterations in hepatobiliary transporters are known to play a role. The disease manifests at the age of approximately 40 years, mainly in men with clinical and laboratory features of cholestasis but may also be asymptomatic. There are specific forms in which the small intrahepatic bile ducts are involved, mainly affecting children, as well as overlap syndromes with autoimmune hepatitis. A form characterized by an increase in IgG4 has been described, which is usually associated with autoimmune pancreatitis. The key diagnostic procedure is endoscopic retrograde cholangiography, although magnetic resonance cholangiography is the first diagnostic procedure that should be used since it is equally informative and non-invasive. Liver biopsy is not essential for diagnosis. Primary sclerosing cholangitis is a progressive disease with a probability of transplant-free survival of 18 years in asymptomatic forms and of 8.5 years in symptomatic forms. Cholangiocarcinoma can result from the disease and confers a poor prognosis. There is no specific treatment although ursodeoxycholic acid improves the biochemical alterations of cholestasis. Liver transplantation is the last therapeutic resort with good results in terms of survival although the disease can recur in the transplanted liver." @default.
• W2022793859 created "2016-06-24" @default.
• W2022793859 creator A5083542745 @default.
• W2022793859 date "2011-01-01" @default.
• W2022793859 modified "2023-09-24" @default.
• W2022793859 title "Colangitis esclerosante primaria: diagnóstico, pronóstico y tratamiento" @default.
• W2022793859 cites W1594113547 @default.
• W2022793859 cites W1646598600 @default.
• W2022793859 cites W1665267469 @default.
• W2022793859 cites W1851143213 @default.
• W2022793859 cites W1868512026 @default.
• W2022793859 cites W1940203697 @default.
• W2022793859 cites W1964156264 @default.
• W2022793859 cites W1967176155 @default.
• W2022793859 cites W1968221120 @default.
• W2022793859 cites W1968970101 @default.
• W2022793859 cites W1969516366 @default.
• W2022793859 cites W1972628599 @default.
• W2022793859 cites W1975044459 @default.
• W2022793859 cites W1975213560 @default.
• W2022793859 cites W1977949495 @default.
• W2022793859 cites W1983442202 @default.
• W2022793859 cites W1989374267 @default.
• W2022793859 cites W1989552765 @default.
• W2022793859 cites W1990009807 @default.
• W2022793859 cites W1990013812 @default.
• W2022793859 cites W1990281867 @default.
• W2022793859 cites W1993535010 @default.
• W2022793859 cites W1994890283 @default.
• W2022793859 cites W1996463505 @default.
• W2022793859 cites W1997112298 @default.
• W2022793859 cites W1997771893 @default.
• W2022793859 cites W1998813362 @default.
• W2022793859 cites W1999929273 @default.
• W2022793859 cites W2001751275 @default.
• W2022793859 cites W2002537558 @default.
• W2022793859 cites W2003679034 @default.
• W2022793859 cites W2005649558 @default.
• W2022793859 cites W2005901103 @default.
• W2022793859 cites W2006412887 @default.
• W2022793859 cites W2006750223 @default.
• W2022793859 cites W2010041570 @default.
• W2022793859 cites W2010198501 @default.
• W2022793859 cites W2011544949 @default.
• W2022793859 cites W2013091990 @default.
• W2022793859 cites W2013504081 @default.
• W2022793859 cites W2014346416 @default.
• W2022793859 cites W2015482578 @default.
• W2022793859 cites W2016020580 @default.
• W2022793859 cites W2019122570 @default.
• W2022793859 cites W2024645140 @default.
• W2022793859 cites W2024945715 @default.
• W2022793859 cites W2026781960 @default.
• W2022793859 cites W2034354903 @default.
• W2022793859 cites W2035142444 @default.
• W2022793859 cites W2035258306 @default.
• W2022793859 cites W2036092291 @default.
• W2022793859 cites W2036657452 @default.
• W2022793859 cites W2045122920 @default.
• W2022793859 cites W2046653318 @default.
• W2022793859 cites W2046724686 @default.
• W2022793859 cites W2048437293 @default.
• W2022793859 cites W2049914976 @default.
• W2022793859 cites W2057504108 @default.
• W2022793859 cites W2059457551 @default.
• W2022793859 cites W2059819368 @default.
• W2022793859 cites W2061887879 @default.
• W2022793859 cites W2067824709 @default.
• W2022793859 cites W2072773805 @default.
• W2022793859 cites W2073485174 @default.
• W2022793859 cites W2073627942 @default.
• W2022793859 cites W2075350279 @default.
• W2022793859 cites W2082233301 @default.
• W2022793859 cites W2082789659 @default.
• W2022793859 cites W2086537746 @default.
• W2022793859 cites W2087379213 @default.
• W2022793859 cites W2087439101 @default.
• W2022793859 cites W2089776122 @default.
• W2022793859 cites W2090645357 @default.
• W2022793859 cites W2092207021 @default.
• W2022793859 cites W2094166732 @default.
• W2022793859 cites W2094783500 @default.
• W2022793859 cites W2095272229 @default.
• W2022793859 cites W2098453507 @default.
• W2022793859 cites W2099482902 @default.
• W2022793859 cites W2111543509 @default.
• W2022793859 cites W2112067172 @default.
• W2022793859 cites W2112227290 @default.
• W2022793859 cites W2112729056 @default.
• W2022793859 cites W2113578436 @default.
• W2022793859 cites W2118422146 @default.
• W2022793859 cites W2125532560 @default.
• W2022793859 cites W2125763073 @default.
• W2022793859 cites W2125944174 @default.
• W2022793859 cites W2130224571 @default.
• W2022793859 cites W2131096427 @default.
• W2022793859 cites W2133403920 @default.
• W2022793859 cites W2134410264 @default.

• next