Matches in SemOpenAlex for { <https://semopenalex.org/work/W2022795375> ?p ?o ?g. }
- W2022795375 endingPage "648" @default.
- W2022795375 startingPage "643" @default.
- W2022795375 abstract "Abstract It is quite apparent that the incidence of neurodegenerative diseases in both men and women increases in a logarithmic fashion with age and begins to rise much more rapidly after the age of 60. Brain aging is accompanied by structural and functional changes at cellular and tissue levels such as increase in free radical generation, lowered antioxidant defenses, decrease in number of neurons, decrease in the activities of enzymes, (g) decrease in impulse transmission. The present study was aimed to assess the neuromodulatory role of Glutathione monoester (GME) when administered intraperitoneally (12 mg/kg body weight) for 20 days on acetylcholine esterase (AchE) activity, levels of neurotransmitters such as dopamine, serotonin, norepinephrine and rotorod behavioral analysis in discrete brain regions of young and aged male albino Wistar rats. Age‐related decrease ( p < 0.05) in acetylcholine esterase activity, neurotransmitter levels and also decrease in sensorimotor performance was observed. GME administration was effective in restoring these neuronal parameters in aged rat brain regions. Thus GME act as a neuromodulator in discrete brain regions of aged rats." @default.
- W2022795375 created "2016-06-24" @default.
- W2022795375 creator A5033814400 @default.
- W2022795375 creator A5050062122 @default.
- W2022795375 creator A5066562872 @default.
- W2022795375 date "2009-08-12" @default.
- W2022795375 modified "2023-09-27" @default.
- W2022795375 title "Role of Glutathione monoester on age‐related neurochemical alterations in rat brain" @default.
- W2022795375 cites W1589787827 @default.
- W2022795375 cites W1658682427 @default.
- W2022795375 cites W1684853394 @default.
- W2022795375 cites W1963556992 @default.
- W2022795375 cites W1964469142 @default.
- W2022795375 cites W1968329600 @default.
- W2022795375 cites W1968812762 @default.
- W2022795375 cites W1971048984 @default.
- W2022795375 cites W1987855116 @default.
- W2022795375 cites W1992152852 @default.
- W2022795375 cites W1992222048 @default.
- W2022795375 cites W1998294088 @default.
- W2022795375 cites W2007617786 @default.
- W2022795375 cites W2016302324 @default.
- W2022795375 cites W2016514911 @default.
- W2022795375 cites W2016728988 @default.
- W2022795375 cites W2019983337 @default.
- W2022795375 cites W2028155510 @default.
- W2022795375 cites W2030954516 @default.
- W2022795375 cites W2034657229 @default.
- W2022795375 cites W2035426975 @default.
- W2022795375 cites W2039385370 @default.
- W2022795375 cites W2048534671 @default.
- W2022795375 cites W2049660909 @default.
- W2022795375 cites W2052296901 @default.
- W2022795375 cites W2055730774 @default.
- W2022795375 cites W2055912815 @default.
- W2022795375 cites W2058980348 @default.
- W2022795375 cites W2065700794 @default.
- W2022795375 cites W2069926262 @default.
- W2022795375 cites W2072787112 @default.
- W2022795375 cites W2087317917 @default.
- W2022795375 cites W2106482561 @default.
- W2022795375 cites W2129366560 @default.
- W2022795375 cites W2130608569 @default.
- W2022795375 cites W2133451731 @default.
- W2022795375 cites W2137629291 @default.
- W2022795375 cites W2142276934 @default.
- W2022795375 cites W2142291145 @default.
- W2022795375 cites W2160932501 @default.
- W2022795375 cites W2169714384 @default.
- W2022795375 cites W2338170813 @default.
- W2022795375 cites W4238201103 @default.
- W2022795375 cites W2033573616 @default.
- W2022795375 doi "https://doi.org/10.1016/j.ijdevneu.2009.07.010" @default.
- W2022795375 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/19682566" @default.
- W2022795375 hasPublicationYear "2009" @default.
- W2022795375 type Work @default.
- W2022795375 sameAs 2022795375 @default.
- W2022795375 citedByCount "0" @default.
- W2022795375 crossrefType "journal-article" @default.
- W2022795375 hasAuthorship W2022795375A5033814400 @default.
- W2022795375 hasAuthorship W2022795375A5050062122 @default.
- W2022795375 hasAuthorship W2022795375A5066562872 @default.
- W2022795375 hasConcept C126322002 @default.
- W2022795375 hasConcept C134018914 @default.
- W2022795375 hasConcept C169760540 @default.
- W2022795375 hasConcept C170493617 @default.
- W2022795375 hasConcept C181199279 @default.
- W2022795375 hasConcept C185592680 @default.
- W2022795375 hasConcept C25876315 @default.
- W2022795375 hasConcept C2775864247 @default.
- W2022795375 hasConcept C2775910092 @default.
- W2022795375 hasConcept C2776219046 @default.
- W2022795375 hasConcept C2778514916 @default.
- W2022795375 hasConcept C2778816929 @default.
- W2022795375 hasConcept C2779059548 @default.
- W2022795375 hasConcept C513476851 @default.
- W2022795375 hasConcept C522857546 @default.
- W2022795375 hasConcept C529278444 @default.
- W2022795375 hasConcept C538909803 @default.
- W2022795375 hasConcept C55493867 @default.
- W2022795375 hasConcept C71924100 @default.
- W2022795375 hasConcept C86803240 @default.
- W2022795375 hasConceptScore W2022795375C126322002 @default.
- W2022795375 hasConceptScore W2022795375C134018914 @default.
- W2022795375 hasConceptScore W2022795375C169760540 @default.
- W2022795375 hasConceptScore W2022795375C170493617 @default.
- W2022795375 hasConceptScore W2022795375C181199279 @default.
- W2022795375 hasConceptScore W2022795375C185592680 @default.
- W2022795375 hasConceptScore W2022795375C25876315 @default.
- W2022795375 hasConceptScore W2022795375C2775864247 @default.
- W2022795375 hasConceptScore W2022795375C2775910092 @default.
- W2022795375 hasConceptScore W2022795375C2776219046 @default.
- W2022795375 hasConceptScore W2022795375C2778514916 @default.
- W2022795375 hasConceptScore W2022795375C2778816929 @default.
- W2022795375 hasConceptScore W2022795375C2779059548 @default.
- W2022795375 hasConceptScore W2022795375C513476851 @default.
- W2022795375 hasConceptScore W2022795375C522857546 @default.
- W2022795375 hasConceptScore W2022795375C529278444 @default.