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- W2022795842 abstract "Abstract Case report A 64 year-old female with Parkinson disease treated with amantadine for two years who suddenly suffered bilateral corneal oedema. It was initially treated as herpetic endotheliitis without improvement as we lacked information on her chronic treatment. The corneal oedema finally resolved after withdrawing the drug. Discussion Amantadine hydrochloride may produce endothelial dysfunction. Once the amantadine treatment is stopped, the corneal oedema may be reversible but endothelial density remains low. An ophthalmologist examination should be performed before the initiation of amantadine treatment in order to establish a risk: benefit ratio, especially in those patients with low endothelial density or any endothelial anomaly." @default.
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- W2022795842 date "2012-09-01" @default.
- W2022795842 modified "2023-10-17" @default.
- W2022795842 title "Corneal toxicity due to amantadine" @default.
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- W2022795842 doi "https://doi.org/10.1016/j.oftale.2011.09.005" @default.
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