Matches in SemOpenAlex for { <https://semopenalex.org/work/W2022796673> ?p ?o ?g. }
- W2022796673 endingPage "4260" @default.
- W2022796673 startingPage "4253" @default.
- W2022796673 abstract "Here, we show that the subcellular localization of alpha-like RNA polymerase II core subunit 3 (RPB3) is regulated during muscle differentiation. We have recently demonstrated that the expression of RPB3 is regulated during muscle differentiation and that, inside RNA polymerase II (RNAP II), it is directly involved in contacting regulatory proteins such as the myogenic transcription factor Myogenin and activating transcription factor ATF4. We show for the first time, that RPB3, in addition to its presence and role inside the RNAP II core enzyme, accumulates in the cytoplasm of cycling myogenic cells and migrates to the nucleus upon induction of the differentiation program. Furthermore, using human RPB3 as bait in a yeast two-hybrid system, we have isolated a novel RPB3 cytoplasmic interacting protein, HCR. HCR, previously identified as alpha-helix coiled-coil rod homologue, is one of the psoriasis vulgaris (PV) candidate genes. In cycling myogenic C2C7 cells, we show that the RPB3 protein directly interacts with HCR within the cytoplasm. Finally, knocking down HCR expression by RNA interference, we demonstrate that HCR acts as cytoplasmic docking site for RPB3." @default.
- W2022796673 created "2016-06-24" @default.
- W2022796673 creator A5008099139 @default.
- W2022796673 creator A5008779360 @default.
- W2022796673 creator A5010214359 @default.
- W2022796673 creator A5018886297 @default.
- W2022796673 creator A5030804679 @default.
- W2022796673 creator A5034696022 @default.
- W2022796673 creator A5054703455 @default.
- W2022796673 creator A5057548226 @default.
- W2022796673 creator A5068264215 @default.
- W2022796673 creator A5074228388 @default.
- W2022796673 date "2005-09-15" @default.
- W2022796673 modified "2023-10-04" @default.
- W2022796673 title "RNA Polymerase II subunit 3 is retained in the cytoplasm by its interaction with HCR, the psoriasis vulgaris candidate gene product" @default.
- W2022796673 cites W1608099235 @default.
- W2022796673 cites W1735187387 @default.
- W2022796673 cites W1973817667 @default.
- W2022796673 cites W1983105728 @default.
- W2022796673 cites W1986825997 @default.
- W2022796673 cites W1993807753 @default.
- W2022796673 cites W2005744558 @default.
- W2022796673 cites W2009353230 @default.
- W2022796673 cites W2012285926 @default.
- W2022796673 cites W2013583348 @default.
- W2022796673 cites W2038783205 @default.
- W2022796673 cites W2055698373 @default.
- W2022796673 cites W2081544530 @default.
- W2022796673 cites W2084622414 @default.
- W2022796673 cites W2086660631 @default.
- W2022796673 cites W2090885189 @default.
- W2022796673 cites W2092238955 @default.
- W2022796673 cites W2092631315 @default.
- W2022796673 cites W2094184203 @default.
- W2022796673 cites W2098296304 @default.
- W2022796673 cites W2102782820 @default.
- W2022796673 cites W2105859301 @default.
- W2022796673 cites W2109938502 @default.
- W2022796673 cites W2118479904 @default.
- W2022796673 cites W2126503680 @default.
- W2022796673 cites W2127265198 @default.
- W2022796673 cites W2138048215 @default.
- W2022796673 cites W2149827592 @default.
- W2022796673 cites W2149870504 @default.
- W2022796673 cites W2152289146 @default.
- W2022796673 cites W2160378721 @default.
- W2022796673 cites W2162042193 @default.
- W2022796673 cites W2334981267 @default.
- W2022796673 cites W2402804962 @default.
- W2022796673 doi "https://doi.org/10.1242/jcs.02545" @default.
- W2022796673 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/16141233" @default.
- W2022796673 hasPublicationYear "2005" @default.
- W2022796673 type Work @default.
- W2022796673 sameAs 2022796673 @default.
- W2022796673 citedByCount "21" @default.
- W2022796673 countsByYear W20227966732012 @default.
- W2022796673 countsByYear W20227966732013 @default.
- W2022796673 countsByYear W20227966732014 @default.
- W2022796673 countsByYear W20227966732018 @default.
- W2022796673 countsByYear W20227966732020 @default.
- W2022796673 countsByYear W20227966732021 @default.
- W2022796673 countsByYear W20227966732022 @default.
- W2022796673 countsByYear W20227966732023 @default.
- W2022796673 crossrefType "journal-article" @default.
- W2022796673 hasAuthorship W2022796673A5008099139 @default.
- W2022796673 hasAuthorship W2022796673A5008779360 @default.
- W2022796673 hasAuthorship W2022796673A5010214359 @default.
- W2022796673 hasAuthorship W2022796673A5018886297 @default.
- W2022796673 hasAuthorship W2022796673A5030804679 @default.
- W2022796673 hasAuthorship W2022796673A5034696022 @default.
- W2022796673 hasAuthorship W2022796673A5054703455 @default.
- W2022796673 hasAuthorship W2022796673A5057548226 @default.
- W2022796673 hasAuthorship W2022796673A5068264215 @default.
- W2022796673 hasAuthorship W2022796673A5074228388 @default.
- W2022796673 hasBestOaLocation W20227966731 @default.
- W2022796673 hasConcept C101762097 @default.
- W2022796673 hasConcept C103549609 @default.
- W2022796673 hasConcept C104292427 @default.
- W2022796673 hasConcept C104317684 @default.
- W2022796673 hasConcept C138885662 @default.
- W2022796673 hasConcept C150194340 @default.
- W2022796673 hasConcept C153911025 @default.
- W2022796673 hasConcept C179926584 @default.
- W2022796673 hasConcept C190062978 @default.
- W2022796673 hasConcept C2776449523 @default.
- W2022796673 hasConcept C41895202 @default.
- W2022796673 hasConcept C54355233 @default.
- W2022796673 hasConcept C64350747 @default.
- W2022796673 hasConcept C67705224 @default.
- W2022796673 hasConcept C86803240 @default.
- W2022796673 hasConcept C95444343 @default.
- W2022796673 hasConceptScore W2022796673C101762097 @default.
- W2022796673 hasConceptScore W2022796673C103549609 @default.
- W2022796673 hasConceptScore W2022796673C104292427 @default.
- W2022796673 hasConceptScore W2022796673C104317684 @default.
- W2022796673 hasConceptScore W2022796673C138885662 @default.
- W2022796673 hasConceptScore W2022796673C150194340 @default.
- W2022796673 hasConceptScore W2022796673C153911025 @default.