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- W2022807165 abstract "Postoperative prophylaxis of venous thromboembolism (VTE) with rivaroxaban (R) is proven to be almost as effective and safe as low-molecular-weight heparin (LWMH) for following primary elective total knee (TKR) and hip replacement (THR) surgery. R is excreted to about 30% by the kidneys into the urine. Decrease of creatinine clearance (CC) may have an impact of the outcome of patients. CC decreases with age. We have developed a method to determine R in serum and urine. The aim of the study was to investigate R excreted into the urine in the postoperative phase and to analyse a relation of plasma, serum and urine concentration of R to age and CC of patients." @default.
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- W2022807165 date "2012-10-01" @default.
- W2022807165 modified "2023-10-16" @default.
- W2022807165 title "C0190 Influence of age and renal function on the concentration of rivaroxaban in plasma and urine in patients undergoing primary elective total knee and hip replacement surgery" @default.
- W2022807165 doi "https://doi.org/10.1016/j.thromres.2012.08.038" @default.
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