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- W2022809164 abstract "The molecular weight of myosin has been determined in 0.5 M KCl and 5 M guanidine · HCl. 1. The molecular weight, using the Archibald approach to equilibrium method is strongly dependent on protein concentration in both solvents giving infinite dilution values of 6.19·105 in 0.5 M KCl and 2.06·105 in 5 M guanidine·HCl. 2. Sedimentation, diffusion and viscosity studies on myosin in 5 M guanidine·HCl provide estimates of the molecular weight in reasonable agreement with the Archibald studies. 3. Preferential binding of guanidine·HCl by myosin has been determined and shown to be of the order of 5% or less. 4. Utilizing these molecular weight determinations and available X-ray diffraction, light scattering and optical rotatory data, a model for the myosin molecule is proposed, based on three equal weight polypeptide chains in the form of a three-stranded α rope." @default.
- W2022809164 created "2016-06-24" @default.
- W2022809164 creator A5054119630 @default.
- W2022809164 creator A5061309118 @default.
- W2022809164 date "1960-07-01" @default.
- W2022809164 modified "2023-09-25" @default.
- W2022809164 title "A model for the myosin molecule" @default.
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- W2022809164 doi "https://doi.org/10.1016/0006-3002(60)90037-8" @default.
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