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- W2022816093 abstract "Lymphogenic Metastatic Spread of Operated Rectal Carcinomas The aim of this study was to determine the risks of local surgery of rectal carcinoma regarding lymphogenic metastatic spread. The appearance of lymphatic metastases in 290 patients suffering from rectal carcinoma was investigated retrospectively. 112 of 290 patients revealed secondary malignancies at the time of operation. 66 patients showed single lymphatic lesions (pN1: 35, pN2: 31), 17 patients had single hematogenous lesions, and 29 patients showed both lymphatic and hematogenous metastases (pN1: 11, pN2: 18). Proximally involved lymph nodes were preferably nodes located near the superior rectal artery and at the inferior mesenteric artery; furthermore, a small number of lateral-iliacal lymph nodes were positive. In 4 cases, lymphatic metastases along the superior rectal artery were found, whereas the local lymph nodes at the tumor were free of any lesions. Low-risk tumors (with little risk of lymphatic metastasis and possible local surgery) had the following features: 1. T-stage: (p)Tis; (p)T1; in case of G1 also (p)T2; 2. Grading: highly differentiated (G1), (G2 questionable); 3. No vessel infiltration; 4. M and N negative (no enlargement of lymph nodes); 5. Tumor size: length < 2 cm, width < 1 cm, deepth < 0.5 cm, diameter < 2 cm, volume < 1 cm3; 6. Normal preoperative CEA and CA 19-9; 7. Recommended safety distance of 5–10 mm in cases of local resection. Local surgical procedures are recommended at special indications as above. However, they bear the potential risk of nonradical surgery and an incomplete staging, and there is a need for careful follow-up examinations." @default.
- W2022816093 created "2016-06-24" @default.
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- W2022816093 date "2002-01-01" @default.
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- W2022816093 title "Lymphogene Metastasierung operierter Rektumkarzinome" @default.
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- W2022816093 doi "https://doi.org/10.1159/000051350" @default.
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