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- W2022823046 abstract "It has been shown that radioactively labeled glucuronic acid and N-acetylgalactosamine are incorporated into a glycosaminoglycan (mucopolysaccharide) when labeled uridine diphosphate glucuronic acid and uridine diphosphate N-acetylgalactosamine are incubated with a microsomal preparation from chick embryo epiphyseal cartilage (Silbert, 1964; Perlman etal., 1964). This glycosaminoglycan has been identified by sugar analysis as the nonsulfated compound chondroitin (Silbert, 1964). The same microsomal preparation has also been shown to contain particle-bound chondroitin sulfate, and to be able to catalyze the incorporation of labeled sulfate from PAPS into this particlebound chondroitin sulfate (DeLuca and Silbert, 1968). This suggests that the synthesis of the polysaccharide chain of chondroitin and sulfation to form the complete chondroitin sulfate product might take place with the same microsomal preparation. The present report describes the use of this microsomal preparation from chick embryo epiphyseal cartilage to form chondroitin sulfate." @default.
- W2022823046 created "2016-06-24" @default.
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- W2022823046 date "1968-06-01" @default.
- W2022823046 modified "2023-09-27" @default.
- W2022823046 title "Formation of chondroitin sulfate by a microsomal preparation from chick embryo epiphyseal cartilage" @default.
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- W2022823046 doi "https://doi.org/10.1016/0006-291x(68)90551-2" @default.
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