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- W2022823596 abstract "A case of diffuse-type tenosynovial giant cell tumor arising in the left upper extremity is reported in a 23-year-old man with neurofibromatosis type 1 (NF1)-Noonan syndrome. The predominately mononuclear cellular proliferation with psammomatous calcifications had the immunohistochemical and ultrastructural features of a fibrohistiocytic neoplasm. This uncommon type of soft tissue neoplasm occurring in this unique clinical setting served to open an inquiry into the subject of non-neurogenic tumors in association with NF1 and Noonan syndrome, both manifested in our patient. Nonossifying fibroma of bone as a presumptive fibrohistiocytic tumor is an uncommon but well-documented manifestation in NF1, whereas in Noonan-like syndrome, both giant cell granuloma and pigmented villonodular synovitis are recognized as associated lesions with histologic and immunophenotypic similarities with the diffuse-type tenosynovial giant cell tumor." @default.
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- W2022823596 date "2006-06-01" @default.
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- W2022823596 title "Diffuse-type Tenosynovial Giant Cell Tumor in Association With Neurofibromatosis Type 1-Noonan Syndrome: Possibly More Than a Chance Relationship" @default.
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- W2022823596 doi "https://doi.org/10.1097/00000478-200606000-00009" @default.
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