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- W2022828947 abstract "Glyco oligonucleotide conjugates, each exhibiting two mannose and two galactose residues, were efficiently synthesized by two successive 1,3-dipolar cycloadditions (click chemistry). Two phosphoramidite derivatives were used: one bearing a bromoalkyl group as a precursor to azide functionalization and another bearing a propargyl group. After a first cycloaddition with a mannosyl-azide derivative, the bromine atoms were substituted with NaN3 and a second click reaction was performed with a 1′-O-propargyl galactose, affording the heteroglyco oligonucleotide conjugate." @default.
- W2022828947 created "2016-06-24" @default.
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- W2022828947 date "2009-01-05" @default.
- W2022828947 modified "2023-10-14" @default.
- W2022828947 title "Synthesis of Mannose and Galactose Oligonucleotide Conjugates by Bi-click chemistry" @default.
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- W2022828947 doi "https://doi.org/10.1021/jo802536q" @default.
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