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• W2022831783 startingPage "4831" @default.
• W2022831783 abstract "Piperazine and (R)-2-(aminomethyl)pyrrolidine derivatives of [1,2,4]triazolo[1,5-a][1,3,5]triazine have recently been shown to be potent and selective adenosine A2a receptor antagonists. We have replaced the triazolotriazine core structure with two different heterocyclic cores. One of these, the one deriving from [1,2,4]triazolo[1,5-c]pyrimidine, appears to be particularly effective and selected analogs from this series have been shown to be orally active in a mouse catalepsy model of Parkinson’s disease." @default.
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• W2022831783 date "2004-10-01" @default.
• W2022831783 modified "2023-10-12" @default.
• W2022831783 title "Studies on adenosine A2a receptor antagonists: comparison of three core heterocycles" @default.
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• W2022831783 doi "https://doi.org/10.1016/j.bmcl.2004.07.047" @default.
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