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- W2022834432 abstract "To report selected dietary intake and vitamin status at baseline of volunteers participating in the ZENITH study and the correlation of vitamin status with zinc. A multicentre prospective intervention study employing a randomised double-blind design. Clermont-Ferrand, Theix (France), Coleraine (Northern Ireland), Grenoble (France), Rome (Italy). In total, 387 healthy middle-aged (55–70 y) and older (70–87 y) men and women participated in the study. Dietary intake was assessed by means of a validated 4-d recall record. Fasting blood samples were simultaneously analysed for retinol and α-tocopherol by the HLPC method. Erythrocyte folates were measured by a competitive immunoassay with direct chemiluminescence detection on an automatised immunoanalyser. In all centres, men had a significantly (P<0.0001) higher mean nutrient intake than women. Comparison between age-groups showed that older individuals had significantly lower intakes of macro- and selected micronutrients than middle-aged subjects (P<0.0001). A high fat intake (from 36 to 40% of total energy) was observed in all examined groups. In relation to biochemical measures of vitamin status, all parameters were above their respective cut-off values for normality and, thus, none of the subjects had biochemical evidence of deficiency of these selected vitamins. A moderate correlation was found with plasma vitamin A and serum zinc (r=0.12, P<0.05) or red blood cell zinc (r=0.12, P<0.01) and with erythrocyte folates and red blood cell zinc (r=0.11, P<0.05). There were only moderate differences in the nutrient intake of the ZENITH study volunteers among the four European centres. Their biochemical status for retinol, α-tocopherol and folate appeared adequate. The ZENITH study is supported by the European Commission ‘Quality of Life and Management of Living Resources’, Fifth Framework Programme, Contract no. QLK1-CT-2001-00168." @default.
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- W2022834432 date "2005-10-28" @default.
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- W2022834432 title "Estimation of intake and status of vitamin A, vitamin E and folate in older European adults: the ZENITH" @default.
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- W2022834432 doi "https://doi.org/10.1038/sj.ejcn.1602297" @default.
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