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- W2022834543 abstract "The paper describes the synthesis of glucose-configured sugar-lysine chimeras in which the side chain of lysine is conformationally constrained via incorporation into a D-glucose scaffold. Key step in the synthesis is a high-yielding, reductive ring opening of an exocyclic glucose-derived epoxide to form an α-hydroxyester that can be converted into chimeric sugar-lysine analogues. To demonstrate the use of these novel chimeric sugar-lysine building blocks in peptide coupling, we replaced D-lysine in the antimicrobial dipeptide sequence kW by a D-glucose-D-lysine chimera." @default.
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- W2022834543 date "2007-02-01" @default.
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- W2022834543 title "Synthesis of Sugar-Lysine Chimera with Integrated gluco-Configured 1,3-Hydroxyamine Motif" @default.
- W2022834543 doi "https://doi.org/10.1055/s-2007-968002" @default.
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