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- W2022841027 abstract "From the leaves of Monotes engleri, five prenylated flavanones were isolated as constituents that displayed cytotoxic activity against several human cancer cell lines. Three of these substances are novel, namely, 6-(1,1-dimethylallyl)naringenin, 6-(1,1-dimethylallyl)eriodictyol and 3′-O-methyl-6-(1,1-dimethylallyl)eriodictyol, with the other two active substances being the known flavanones, 6,8-diprenyleriodictyol and hiravanone. Additionally, two novel, but non-cytotoxic, biogenetically related flavanones were isolated, 6-[(2RS)-hydroxy-3-methyl-3-butenyl]-8-prenyleriodictyol and 5,4′-dihydroxy-4″,4″-dimethyl-5″-methyl-5″H-dihydrofurano[2″,3″:6,7]flavanone. The structures of the new compounds were determined by spectral analysis 1D- and 2D-NMR experiments." @default.
- W2022841027 created "2016-06-24" @default.
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- W2022841027 date "1997-06-01" @default.
- W2022841027 modified "2023-10-16" @default.
- W2022841027 title "Cytotoxic prenylated flavanones from Monotes engleri" @default.
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- W2022841027 doi "https://doi.org/10.1016/s0031-9422(96)00871-0" @default.
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