Matches in SemOpenAlex for { <https://semopenalex.org/work/W2022841439> ?p ?o ?g. }
- W2022841439 endingPage "1827" @default.
- W2022841439 startingPage "1817" @default.
- W2022841439 abstract "The homeobox gene Noto is expressed in the node and its derivative the notochord. Here we use a targeted Noto-GFP reporter to isolate and characterize node/notochord-like cells derived from mouse embryonic stem cells. We find very few Noto-expressing cells after spontaneous differentiation. However, the number of Noto-expressing cells was increased when using Activin A to induce a Foxa2- and Brachyury-expressing progenitor population, whose further differentiation into Noto-expressing cells was improved by simultaneous inhibition of BMP, Wnt, and retinoic acid signaling. Noto-GFP+ cells expressed the node/notochord markers Noto, Foxa2, Shh, Noggin, Chordin, Foxj1, and Brachyury; showed a vacuolarization characteristic of notochord cells; and can integrate into midline structures when grafted into Hensen's node of gastrulating chicken embryos. The ability to generate node/notochord-like cells in vitro will aid the biochemical characterization of these developmentally important structures." @default.
- W2022841439 created "2016-06-24" @default.
- W2022841439 creator A5006662295 @default.
- W2022841439 creator A5008188163 @default.
- W2022841439 creator A5040352573 @default.
- W2022841439 creator A5051845029 @default.
- W2022841439 date "2011-11-01" @default.
- W2022841439 modified "2023-09-23" @default.
- W2022841439 title "Isolation and Characterization of Node/Notochord-Like Cells from Mouse Embryonic Stem Cells" @default.
- W2022841439 cites W1616656317 @default.
- W2022841439 cites W1651423553 @default.
- W2022841439 cites W1657005131 @default.
- W2022841439 cites W1844312938 @default.
- W2022841439 cites W1844743435 @default.
- W2022841439 cites W1959009706 @default.
- W2022841439 cites W1966507577 @default.
- W2022841439 cites W1969859127 @default.
- W2022841439 cites W1982087641 @default.
- W2022841439 cites W1982168739 @default.
- W2022841439 cites W1984696112 @default.
- W2022841439 cites W1985222746 @default.
- W2022841439 cites W1988188677 @default.
- W2022841439 cites W1988547053 @default.
- W2022841439 cites W1992949513 @default.
- W2022841439 cites W1993000387 @default.
- W2022841439 cites W1998338586 @default.
- W2022841439 cites W2002679487 @default.
- W2022841439 cites W2003028861 @default.
- W2022841439 cites W2004196170 @default.
- W2022841439 cites W2009624062 @default.
- W2022841439 cites W2010041789 @default.
- W2022841439 cites W2017382210 @default.
- W2022841439 cites W2017835956 @default.
- W2022841439 cites W2026150045 @default.
- W2022841439 cites W2029279705 @default.
- W2022841439 cites W2041290623 @default.
- W2022841439 cites W2044918998 @default.
- W2022841439 cites W2046254071 @default.
- W2022841439 cites W2053093350 @default.
- W2022841439 cites W2054471432 @default.
- W2022841439 cites W2058010162 @default.
- W2022841439 cites W2059614045 @default.
- W2022841439 cites W2069014283 @default.
- W2022841439 cites W2070833008 @default.
- W2022841439 cites W2083904901 @default.
- W2022841439 cites W2084981578 @default.
- W2022841439 cites W2085209701 @default.
- W2022841439 cites W2093315651 @default.
- W2022841439 cites W2098385149 @default.
- W2022841439 cites W2100715279 @default.
- W2022841439 cites W2104407051 @default.
- W2022841439 cites W2113629408 @default.
- W2022841439 cites W2117814548 @default.
- W2022841439 cites W2127202275 @default.
- W2022841439 cites W2136633961 @default.
- W2022841439 cites W2136732727 @default.
- W2022841439 cites W2137300901 @default.
- W2022841439 cites W2139020188 @default.
- W2022841439 cites W2142986021 @default.
- W2022841439 cites W2148272837 @default.
- W2022841439 cites W2153883180 @default.
- W2022841439 cites W2163511428 @default.
- W2022841439 cites W2165981305 @default.
- W2022841439 cites W2166870017 @default.
- W2022841439 cites W2168583421 @default.
- W2022841439 cites W2212593511 @default.
- W2022841439 doi "https://doi.org/10.1089/scd.2011.0042" @default.
- W2022841439 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3928718" @default.
- W2022841439 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/21351873" @default.
- W2022841439 hasPublicationYear "2011" @default.
- W2022841439 type Work @default.
- W2022841439 sameAs 2022841439 @default.
- W2022841439 citedByCount "22" @default.
- W2022841439 countsByYear W20228414392013 @default.
- W2022841439 countsByYear W20228414392014 @default.
- W2022841439 countsByYear W20228414392015 @default.
- W2022841439 countsByYear W20228414392016 @default.
- W2022841439 countsByYear W20228414392018 @default.
- W2022841439 countsByYear W20228414392019 @default.
- W2022841439 countsByYear W20228414392020 @default.
- W2022841439 countsByYear W20228414392021 @default.
- W2022841439 countsByYear W20228414392022 @default.
- W2022841439 countsByYear W20228414392023 @default.
- W2022841439 crossrefType "journal-article" @default.
- W2022841439 hasAuthorship W2022841439A5006662295 @default.
- W2022841439 hasAuthorship W2022841439A5008188163 @default.
- W2022841439 hasAuthorship W2022841439A5040352573 @default.
- W2022841439 hasAuthorship W2022841439A5051845029 @default.
- W2022841439 hasBestOaLocation W20228414392 @default.
- W2022841439 hasConcept C104317684 @default.
- W2022841439 hasConcept C129536746 @default.
- W2022841439 hasConcept C137620995 @default.
- W2022841439 hasConcept C144024400 @default.
- W2022841439 hasConcept C145103041 @default.
- W2022841439 hasConcept C149923435 @default.
- W2022841439 hasConcept C196843134 @default.
- W2022841439 hasConcept C201750760 @default.
- W2022841439 hasConcept C2776133846 @default.