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- W2022843429 abstract "In a controlled trial, a hypotonic oral rehydration solution (ORS) (Na+67, K+20, CP66, citrate 7, glucose 89mmol/1 osmolality 249 mosmol/kg) was compared with a standard WHO-ORS (Na+90, K+20, Cl-80, citrate 10, glucose lllmmol/1, osmolality 311 mosmol/kg) in 60 children aged 5-24 months with acute watery diarrhoea. In the hypotonic ORS group, stool frequency, proportion of children who vomited, ORS requirements and purging rate over 24-48 h were reduced by 33% (p= 0.01), 30% (p= 0.02), 21% (p= 0.067) and 21% (p = 0.03), respectively. The proportion of children who vomited and the purging rate over 48 h were reduced by 23% (p= 0.03) and 10% (p= 0.097), respectively. Serum electrolytes after 48 h were comparable. The beneficial effect of hypotonic ORS was most marked in, and largely contributed by, the subgroup negative for rotavirus." @default.
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- W2022843429 date "1995-03-01" @default.
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- W2022843429 title "Hypotonic oral rehydration solution in acute diarrhoea: a controlled clinical trial" @default.
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- W2022843429 doi "https://doi.org/10.1111/j.1651-2227.1995.tb13630.x" @default.
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