FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2022844594> ?p ?o ?g. }

• W2022844594 endingPage "11" @default.
• W2022844594 startingPage "7" @default.
• W2022844594 abstract "The most dangerous and life-threatening manifestation of allergic diseases is anaphylaxis, a condition in which the cardiovascular system is responsible for the majority of clinical symptoms and for potentially fatal outcome. The heart is both a source and a target of chemical mediators released during allergic reactions. Mast cells are abundant in the human heart, where they are located predominantly around the adventitia of large coronary arteries and in close contact with the small intramural vessels. Cardiac mast cells can be activated by a variety of stimuli including allergens, complement factors, general anesthetics and muscle relaxants. Mediators released from immunologically activated human heart mast cells strongly influence ventricular function, cardiac rhythm and coronary artery tone. Histamine, cysteinyl leukotrienes and platelet-activating factor (PAF) exert negative inotropic effects and induce myocardial depression that contribute significantly to the pathogenesis of anaphylactic shock. Moreover, cardiac mast cells release chymase and renin that activates the angiotensin system locally, which further induces arteriolar vasoconstriction. The number and density of cardiac mast cells is increased in patients with ischaemic heart disease and dilated cardiomyopathies. This observation may help explain why these conditions are major risk factors for fatal anaphylaxis. A better understanding of the mechanisms involved in cardiac mast cell activation may lead to an improvement in prevention and treatment of systemic anaphylaxis." @default.
• W2022844594 created "2016-06-24" @default.
• W2022844594 creator A5004116646 @default.
• W2022844594 creator A5040903631 @default.
• W2022844594 creator A5044096444 @default.
• W2022844594 creator A5079235615 @default.
• W2022844594 creator A5089722463 @default.
• W2022844594 date "2008-07-21" @default.
• W2022844594 modified "2023-09-23" @default.
• W2022844594 title "Allergy and the cardiovascular system" @default.
• W2022844594 cites W1562920790 @default.
• W2022844594 cites W1605729830 @default.
• W2022844594 cites W1969815811 @default.
• W2022844594 cites W1972029596 @default.
• W2022844594 cites W1977352338 @default.
• W2022844594 cites W1982584865 @default.
• W2022844594 cites W1983622936 @default.
• W2022844594 cites W1994592677 @default.
• W2022844594 cites W2001473701 @default.
• W2022844594 cites W2009221517 @default.
• W2022844594 cites W2009978724 @default.
• W2022844594 cites W2017165868 @default.
• W2022844594 cites W2024243414 @default.
• W2022844594 cites W2025910632 @default.
• W2022844594 cites W2028999452 @default.
• W2022844594 cites W2030066805 @default.
• W2022844594 cites W2034417693 @default.
• W2022844594 cites W2042423928 @default.
• W2022844594 cites W2055159267 @default.
• W2022844594 cites W2062680473 @default.
• W2022844594 cites W2069799994 @default.
• W2022844594 cites W2071324084 @default.
• W2022844594 cites W2072361073 @default.
• W2022844594 cites W2077454191 @default.
• W2022844594 cites W2085577106 @default.
• W2022844594 cites W2086848165 @default.
• W2022844594 cites W2093529460 @default.
• W2022844594 cites W2099509454 @default.
• W2022844594 cites W2113434905 @default.
• W2022844594 cites W2114765674 @default.
• W2022844594 cites W2137385183 @default.
• W2022844594 cites W2138694854 @default.
• W2022844594 cites W2142459344 @default.
• W2022844594 cites W2146968394 @default.
• W2022844594 cites W2161473158 @default.
• W2022844594 cites W4229620302 @default.
• W2022844594 doi "https://doi.org/10.1111/j.1365-2249.2008.03714.x" @default.
• W2022844594 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2515352" @default.
• W2022844594 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/18721322" @default.
• W2022844594 hasPublicationYear "2008" @default.
• W2022844594 type Work @default.
• W2022844594 sameAs 2022844594 @default.
• W2022844594 citedByCount "130" @default.
• W2022844594 countsByYear W20228445942012 @default.
• W2022844594 countsByYear W20228445942013 @default.
• W2022844594 countsByYear W20228445942014 @default.
• W2022844594 countsByYear W20228445942015 @default.
• W2022844594 countsByYear W20228445942016 @default.
• W2022844594 countsByYear W20228445942017 @default.
• W2022844594 countsByYear W20228445942018 @default.
• W2022844594 countsByYear W20228445942019 @default.
• W2022844594 countsByYear W20228445942020 @default.
• W2022844594 countsByYear W20228445942021 @default.
• W2022844594 countsByYear W20228445942022 @default.
• W2022844594 countsByYear W20228445942023 @default.
• W2022844594 crossrefType "journal-article" @default.
• W2022844594 hasAuthorship W2022844594A5004116646 @default.
• W2022844594 hasAuthorship W2022844594A5040903631 @default.
• W2022844594 hasAuthorship W2022844594A5044096444 @default.
• W2022844594 hasAuthorship W2022844594A5079235615 @default.
• W2022844594 hasAuthorship W2022844594A5089722463 @default.
• W2022844594 hasBestOaLocation W20228445941 @default.
• W2022844594 hasConcept C1122143 @default.
• W2022844594 hasConcept C126322002 @default.
• W2022844594 hasConcept C155710745 @default.
• W2022844594 hasConcept C170493617 @default.
• W2022844594 hasConcept C203014093 @default.
• W2022844594 hasConcept C207480886 @default.
• W2022844594 hasConcept C2775933838 @default.
• W2022844594 hasConcept C2779726688 @default.
• W2022844594 hasConcept C2780614898 @default.
• W2022844594 hasConcept C2781372229 @default.
• W2022844594 hasConcept C2781406822 @default.
• W2022844594 hasConcept C49802076 @default.
• W2022844594 hasConcept C500558357 @default.
• W2022844594 hasConcept C71924100 @default.
• W2022844594 hasConceptScore W2022844594C1122143 @default.
• W2022844594 hasConceptScore W2022844594C126322002 @default.
• W2022844594 hasConceptScore W2022844594C155710745 @default.
• W2022844594 hasConceptScore W2022844594C170493617 @default.
• W2022844594 hasConceptScore W2022844594C203014093 @default.
• W2022844594 hasConceptScore W2022844594C207480886 @default.
• W2022844594 hasConceptScore W2022844594C2775933838 @default.
• W2022844594 hasConceptScore W2022844594C2779726688 @default.
• W2022844594 hasConceptScore W2022844594C2780614898 @default.
• W2022844594 hasConceptScore W2022844594C2781372229 @default.
• W2022844594 hasConceptScore W2022844594C2781406822 @default.
• W2022844594 hasConceptScore W2022844594C49802076 @default.

• next